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Vascular Bioactivation of Nitroglycerin by Aldehyde Dehydrogenase-2: REACTION INTERMEDIATES REVEALED BY CRYSTALLOGRAPHY AND MASS SPECTROMETRYBioactivation of nitroglycerin--a new piece in the puzzle.Formation of transient oxygen complexes of cytochrome p450 BM3 and nitric oxide synthase under high pressure.Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient miceAldehyde dehydrogenase-independent bioactivation of nitroglycerin in porcine and bovine blood vesselsATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARα agonist.High-pressure studies of the reaction mechanism of nitric-oxide synthase.Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and L-citrulline formationCardiac oxidative stress in a mouse model of neutral lipid storage disease.Endothelial dysfunction in adipose triglyceride lipase deficiency.Cardioprotective effects of 5-hydroxymethylfurfural mediated by inhibition of L-type Ca(2+) current.Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS).Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling.Vascular bioactivation of nitroglycerin is catalyzed by cytosolic aldehyde dehydrogenase-2.Inefficient spin trapping of superoxide in the presence of nitric-oxide: implications for studies on nitric-oxide synthase uncoupling.Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of nitric oxide.Binding of L-arginine and imidazole suggests heterogeneity of rat brain neuronal nitric oxide synthase.Desensitization of endothelial nitric oxide synthase by receptor agonistsEfficient nitrosation of glutathione by nitric oxide.Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.Partially irreversible inactivation of mitochondrial aldehyde dehydrogenase by nitroglycerin.Effects of nitroglycerin/L-cysteine on soluble guanylate cyclase: evidence for an activation/inactivation equilibrium controlled by nitric oxide binding and haem oxidation.Human Second Window Pre-Conditioning and Post-Conditioning by Nitrite Is Influenced by a Common Polymorphism in Mitochondrial Aldehyde Dehydrogenase.Attenuation of myocardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase.The bell-shaped curve for peroxynitrite-mediated oxidation and nitration of NO/O2-* is alive and well.Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2.Site-directed mutagenesis of aldehyde dehydrogenase-2 suggests three distinct pathways of nitroglycerin biotransformation.Neither nitrite nor nitric oxide mediate toxic effects of nitroglycerin on mitochondria.Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase.Effects of statins on nitric oxide/cGMP signaling in human umbilical vein endothelial cells.Evidence against tetrahydrobiopterin depletion of vascular tissue exposed to nitric oxide/superoxide or nitroglycerin.Mechanisms underlying activation of soluble guanylate cyclase by the nitroxyl donor Angeli's salt.Nitric oxide synthase-I containing cortical interneurons co-express antioxidative enzymes and anti-apoptotic Bcl-2 following focal ischemia: evidence for direct and indirect mechanisms towards their resistance to neuropathology.Antioxidative and myocardial protective effects of L-arginine in oxygen radical-induced injury of isolated perfused rat hearts.Lack of involvement of extracellular signal-regulated kinase (ERK) in the agonist-induced endothelial nitric oxide synthesis.Functional and analytical evidence for scavenging of oxygen radicals by L-arginine.Redox role for tetrahydrobiopterin in nitric oxide synthase catalysis: low-temperature optical absorption spectral detection.Protein tyrosine nitration and peroxynitrite: reply.
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description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
Bernd Mayer
@ast
Bernd Mayer
@en
Bernd Mayer
@es
Bernd Mayer
@nl
Bernd Mayer
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type
label
Bernd Mayer
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Bernd Mayer
@en
Bernd Mayer
@es
Bernd Mayer
@nl
Bernd Mayer
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prefLabel
Bernd Mayer
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Bernd Mayer
@en
Bernd Mayer
@es
Bernd Mayer
@nl
Bernd Mayer
@sl
P106
P21
P31
P496
0000-0002-2921-3494