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TWIK-1 two-pore domain potassium channels change ion selectivity and conduct inward leak sodium currents in hypokalemiaThe 5-HT2 antagonist ketanserin is an open channel blocker of human cardiac ether-à-go-go-related gene (hERG) potassium channels.Molecular determinants of pentamidine-induced hERG trafficking inhibition.Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling.The calmodulin inhibitor N-(6-aminohexyl)-5-chloro-1-naphthalene sulphonamide directly blocks human ether à-go-go-related gene potassium channels stably expressed in human embryonic kidney 293 cells.Intracellular potassium stabilizes human ether-à-go-go-related gene channels for export from endoplasmic reticulum.Exploring the Dynamics of the TWIK-1 Channel.The role of monoubiquitination in endocytic degradation of human ether-a-go-go-related gene (hERG) channels under low K+ conditions.Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant.Linkage between 'disruption of inactivation' and 'reduction of K+ selectivity' among hERG mutants in the S5-P linker region.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Na+ permeation and block of hERG potassium channels.
@en
type
label
Na+ permeation and block of hERG potassium channels.
@en
prefLabel
Na+ permeation and block of hERG potassium channels.
@en
P2860
P356
P1476
Na+ permeation and block of hERG potassium channels.
@en
P2093
Hongying Gang
Shetuan Zhang
P2860
P356
10.1085/JGP.200609500
P577
2006-06-12T00:00:00Z