In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106. - Wikidata - wikimedia - TriplyDB

In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106.

In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106.

http://www.wikidata.org/entity/Q40275502

about

Exploring potential mechanisms of action of natalizumab in secondary progressive multiple sclerosis Precision Medicine in Multiple Sclerosis: Future of PET Imaging of Inflammation and Reactive Astrocytes Imaging neuroinflammation in multiple sclerosis using TSPO-PET Imaging Neuroinflammation - from Bench to Bedside.Recent imaging advances in neurology.Translocator Protein-18 kDa (TSPO) Positron Emission Tomography (PET) Imaging and Its Clinical Impact in Neurodegenerative Diseases A TSPO ligand attenuates brain injury after intracerebral hemorrhage Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.[18F]FEBMP: Positron Emission Tomography Imaging of TSPO in a Model of Neuroinflammation in Rats, and in vitro Autoradiograms of the Human Brain.The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis.Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.In vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [(18)F]GE-180 and effect of docosahexaenoic acid PET imaging in multiple sclerosis.Mapping neuroinflammation in frontotemporal dementia with molecular PET imaging.Spring cleaning: time to rethink imaging research lines in MS?Translocator protein (TSPO) ligands for the diagnosis or treatment of neurodegenerative diseases: a patent review (2010-2015; part 1).Effect of Preventive and Curative Fingolimod Treatment Regimens on Microglia Activation and Disease Progression in a Rat Model of Multiple Sclerosis.A translocator protein 18 kDa agonist protects against cerebral ischemia/reperfusion injury TSPO imaging using the novel PET ligand [18F]GE-180: quantification approaches in patients with multiple sclerosis.18F-GE-180: a novel TSPO radiotracer compared to 11C-R-PK11195 in a preclinical model of stroke.Development of a PET radioligand for potassium channels to image CNS demyelination.The Role of Advanced Magnetic Resonance Imaging Techniques in Multiple Sclerosis Clinical Trials.In vivo imaging of system xc- as a novel approach to monitor multiple sclerosis.Evaluation of Microglial Activation in Multiple Sclerosis Patients Using Positron Emission Tomography.The Place of PET to Assess New Therapeutic Effectiveness in Neurodegenerative Diseases.

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In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106.

http://www.wikidata.org/entity/Q40275502

description

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In vivo TSPO imaging in patien ...... PET study with [18F]FEDAA1106.

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In vivo TSPO imaging in patien ...... PET study with [18F]FEDAA1106.

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In vivo TSPO imaging in patien ...... PET study with [18F]FEDAA1106.

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EJNMMI Research

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In vivo TSPO imaging in patien ...... PET study with [18F]FEDAA1106.

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Akihiro Takano

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Andrea Thiele

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Andrea Varrone

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Anja Hoffmann

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Balázs Gulyás

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Christopher C Rowe

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Fredrik Piehl

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Jan Hillert

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Marcus Schultze-Mosgau

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Nabil Al Tawil

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P2860

An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28

Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects.

Mixed-affinity binding in humans with 18-kDa translocator protein ligands.

Translocator protein PET imaging for glial activation in multiple sclerosis

Translocator protein (18 kDa) polymorphism (rs6971) explains in-vivo brain binding affinity of the PET radioligand [(18)F]-FEPPA.

A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain.

Identifying improved TSPO PET imaging probes through biomathematics: the impact of multiple TSPO binding sites in vivo.

PET visualization of microglia in multiple sclerosis patients using [11C]PK11195.

Development of a new radioligand, N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoroethyl-5-methoxybenzyl)acetamide, for pet imaging of peripheral benzodiazepine receptor in primate brain.

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1

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Christer Halldin

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multiple sclerosis

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