Ebolavirus requires acid sphingomyelinase activity and plasma membrane sphingomyelin for infection.
about
Addressing Therapeutic Options for Ebola Virus Infection in Current and Future OutbreaksInhibition of acid sphingomyelinase by tricyclic antidepressants and analogonsMultiple cationic amphiphiles induce a Niemann-Pick C phenotype and inhibit Ebola virus entry and infectionA screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.Analyses of Entry Mechanisms of Novel Emerging Viruses Using Pseudotype VSV System.Analysis of Lujo virus cell entry using pseudotype vesicular stomatitis virus.High dose sertraline monotherapy fails to protect rhesus macaques from lethal challenge with Ebola virus Makona.Crimean-Congo hemorrhagic fever virus entry into host cells occurs through the multivesicular body and requires ESCRT regulatorsSerum metabolome and lipidome changes in adult patients with primary dengue infection.Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry InhibitorsNeutral sphingomyelinase-2, acid sphingomyelinase, and ceramide levels in COPD patients compared to controlsSelective inhibition of Ebola entry with selective estrogen receptor modulators by disrupting the endolysosomal calcium.The emerging role of acid sphingomyelinase in autophagy.Ebola virus entry into host cells: identifying therapeutic strategies.Cellular Uptake of Clostridium botulinum C2 Toxin Requires Acid Sphingomyelinase ActivityCeramide formation mediated by acid sphingomyelinase facilitates endosomal escape of caliciviruses.Unraveling the role of membrane microdomains during microbial infections.Antiviral activity of cationic amphiphilic drugs.Synergistic drug combination effectively blocks Ebola virus infection.Mechanisms of Filovirus Entry.Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virusAcid sphingomyelinase promotes endothelial stress response in systemic inflammation and sepsis.Altered Clathrin-Independent Endocytosis in Type A Niemann-Pick Disease Cells and Rescue by ICAM-1-Targeted Enzyme DeliveryImipramine blocks acute silicosis in a mouse model.Neutral sphingomyelinase 2 is a key factor for PorB-dependent invasion of Neisseria gonorrhoeae.A Comparative Study on the Alterations of Endocytic Pathways in Multiple Lysosomal Storage Disorders.Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site engineering of sphingomyelin synthases.Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies.Target identification and mode of action of four chemically divergent drugs against Ebola virus infection.Proteomic Profiling Reveals the Transglutaminase-2 Externalization Pathway in Kidneys after Unilateral Ureteric Obstruction.Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site-engineering of sphingomyelin synthases.Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy.Candidate medical countermeasures targeting Ebola virus cell entryRepurposing potential of 1st generation H-specific antihistamines as anti-filovirus therapeutics
P2860
Q26801423-F173CFEB-6D6D-4028-A894-6379A5A76699Q26852322-208E5DB3-098E-4FFE-B1D4-8BD3AFC07CEBQ28486226-12EEA3E4-D44A-49C9-8A36-C5DD40DA2CD6Q30279239-EA8B931C-72B5-467E-8B71-A72B5797D402Q33418872-2D98D62F-0183-4C5F-B5D6-1814A917D37AQ33744103-C444A45E-93F6-46FB-9447-914F1215585BQ33919019-8B953782-E418-478A-B137-E3F671624019Q34215373-6DBFDC5C-9BD1-4F09-ACF7-3964D24540C0Q34965777-E16EA3B5-5491-417D-AB7D-C610CAA02030Q35660156-79069571-3CB8-4D5B-8467-F926878D612AQ36012840-C7605101-E4D6-40A2-829D-21BA3C39F259Q37248481-B192DBA6-9C65-45C4-8E32-5AAC99109C14Q37602125-C57EAB40-A4BA-421E-BE7C-0FB02C90157FQ38349925-CF03CCA0-FD92-4E72-B20F-8C7E6056EF49Q38618148-3C9BF74E-3FF4-4230-A397-28BAEF12B2FDQ38718763-0E7FE78A-31EB-499B-A3E9-1E49FF779147Q38873612-1BDAA756-907A-4479-BDF0-D73EAFA5880FQ39169754-EA8CA898-2738-4E0B-B8F2-FD00B4CC6543Q39175768-E906BCDF-D30E-4E16-82C1-FFC8F778259CQ40078596-6DE35DDD-C61F-452C-AFE9-FD2765CAEAF7Q40164611-940887E3-6EA4-4195-BF68-39507C18454BQ40433618-69AEF5D8-D2E9-4904-81A0-884BDFCCE5A9Q40637739-55259D0E-CCC5-49CA-94B2-01FC69994F15Q41035019-E4FAA8F3-2C49-4AF3-949E-08C660F7DF3DQ41281171-2A764D75-B702-4D0B-9531-8725280B2BF4Q41737964-31D8EF6A-1FF2-436E-AB69-EAB33E9DEF77Q41829569-30D73E72-218D-4B7A-8DAB-D211E9DBF4CCQ41863719-E1285D39-3A73-4FC3-8513-0300C05FB439Q43280688-299D62EA-0904-4925-AB32-4D821B1CAC42Q47260721-23C4B3C6-C9DF-466D-8FB7-964F0845CA4CQ48139494-913496A5-9EFC-4062-A03B-4019E9FE8157Q50948168-017B43F0-6864-4E14-838C-B98895B42040Q53731153-60158A20-B899-4A15-9B38-0ECC7FCD3957Q56763004-683A9679-F818-4D0F-AEC4-115E5E81E53CQ57092053-759EA4DC-31D9-4F21-8A79-08D4D4FFD2E7
P2860
Ebolavirus requires acid sphingomyelinase activity and plasma membrane sphingomyelin for infection.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Ebolavirus requires acid sphin ...... e sphingomyelin for infection.
@en
type
label
Ebolavirus requires acid sphin ...... e sphingomyelin for infection.
@en
prefLabel
Ebolavirus requires acid sphin ...... e sphingomyelin for infection.
@en
P2093
P2860
P356
P1433
P1476
Ebolavirus requires acid sphin ...... e sphingomyelin for infection.
@en
P2093
Andrey A Kolokoltsov
Mary E Miller
Robert A Davey
Shramika Adhikary
P2860
P304
P356
10.1128/JVI.00136-12
P407
P577
2012-05-09T00:00:00Z