A zinc-binding region in Vif binds Cul5 and determines cullin selection. - Wikidata - wikimedia - TriplyDB

A zinc-binding region in Vif binds Cul5 and determines cullin selection.

A zinc-binding region in Vif binds Cul5 and determines cullin selection.

http://www.wikidata.org/entity/Q40288287

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Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1 HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors HIV-1 Vif, APOBEC, and intrinsic immunity A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity Cytidine deamination induced HIV-1 drug resistance The HIV-1 Vif PPLP motif is necessary for human APOBEC3G binding and degradation Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation 7SL RNA mediates virion packaging of the antiviral cytidine deaminase APOBEC3G Viral Mimicry to Usurp Ubiquitin and SUMO Host Pathways Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction The SOCS-box of HIV-1 Vif interacts with ElonginBC by induced-folding to recruit its Cul5-containing ubiquitin ligase complex Characterization of the interaction of full-length HIV-1 Vif protein with its key regulator CBFβ and CRL5 E3 ubiquitin ligase components Structural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB Evidence for selection at HIV host susceptibility genes in a West Central African human population APOBEC3G: an intracellular centurion Multiple ways of targeting APOBEC3-virion infectivity factor interactions for anti-HIV-1 drug development.Polymorphisms of CUL5 are associated with CD4+ T cell loss in HIV-1 infected individuals.Mass spectrometry analysis of HIV-1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity.Identifying determinants of cullin binding specificity among the three functionally different Drosophila melanogaster Roc proteins via domain swapping.Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins Prediction of HIV-1 virus-host protein interactions using virus and host sequence motifs.Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS.Identification of dominant negative human immunodeficiency virus type 1 Vif mutants that interfere with the functional inactivation of APOBEC3G by virus-encoded Vif Identification of 81LGxGxxIxW89 and 171EDRW174 domains from human immunodeficiency virus type 1 Vif that regulate APOBEC3G and APOBEC3F neutralizing activity.Core binding factor beta plays a critical role by facilitating the assembly of the Vif-cullin 5 E3 ubiquitin ligase.Evolutionarily conserved requirement for core binding factor beta in the assembly of the human immunodeficiency virus/simian immunodeficiency virus Vif-cullin 5-RING E3 ubiquitin ligase.Identification of a critical T(Q/D/E)x5ADx2(I/L) motif from primate lentivirus Vif proteins that regulate APOBEC3G and APOBEC3F neutralizing activity.N-terminal hemagglutinin tag renders lysine-deficient APOBEC3G resistant to HIV-1 Vif-induced degradation by reduced polyubiquitination.Small-molecule inhibition of human immunodeficiency virus type 1 replication by targeting the interaction between Vif and ElonginC.Role of cullin-elonginB-elonginC E3 complex in bovine immunodeficiency virus and maedi-visna virus Vif-mediated degradation of host A3Z2-Z3 proteins Core-binding factor subunit beta is not required for non-primate lentiviral Vif-mediated APOBEC3 degradation.Characterization of RNA binding and chaperoning activities of HIV-1 Vif protein. Importance of the C-terminal unstructured tail.Association of potent human antiviral cytidine deaminases with 7SL RNA and viral RNP in HIV-1 virions.Identification of specific determinants of human APOBEC3F, APOBEC3C, and APOBEC3DE and African green monkey APOBEC3F that interact with HIV-1 Vif.Requirement of HIV-1 Vif C-terminus for Vif-CBF-β interaction and assembly of CUL5-containing E3 ligase Multifaceted counter-APOBEC3G mechanisms employed by HIV-1 Vif.On the solution conformation and dynamics of the HIV-1 viral infectivity factor Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complex

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P2860

A zinc-binding region in Vif binds Cul5 and determines cullin selection.

http://www.wikidata.org/entity/Q40288287

description

2006 nî lūn-bûn

@nan

2006年の論文

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2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

@zh

2006年论文

@zh-cn

name

A zinc-binding region in Vif binds Cul5 and determines cullin selection.

@en

type

label

A zinc-binding region in Vif binds Cul5 and determines cullin selection.

@en

prefLabel

A zinc-binding region in Vif binds Cul5 and determines cullin selection.

@en

P1433

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P1433

Journal of Biological Chemistry

P1476

A zinc-binding region in Vif binds Cul5 and determines cullin selection.

@en

P2093

Andrew Mehle

http://www.w3.org/2001/XMLSchema#string

Dana Gabuzda

http://www.w3.org/2001/XMLSchema#string

Elaine R Thomas

http://www.w3.org/2001/XMLSchema#string

Kottampatty S Rajendran

http://www.w3.org/2001/XMLSchema#string

P2860

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery.

Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication

A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins

Production of infectious human immunodeficiency virus type 1 does not require depletion of APOBEC3G from virus-producing cells

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

Function and regulation of cullin-RING ubiquitin ligases

P304

17259-17265

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P31

scholarly article

P356

10.1074/JBC.M602413200

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P407

P433

25

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P478

281

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P577

2006-04-24T00:00:00Z

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P698

16636053

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