Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity.
about
Cytomegalovirus antivirals and development of improved animal modelsIdentification of inhibitors for a virally encoded protein kinase by 2 different screening systems: in vitro kinase assay and in-cell activity assay.Human cytomegalovirus UL97 Kinase is required for the normal intranuclear distribution of pp65 and virion morphogenesisViral and cell cycle-regulated kinases in cytomegalovirus-induced pseudomitosis and replication.The Emerging Roles of Viroporins in ER Stress Response and Autophagy Induction during Virus InfectionConserved herpesvirus protein kinases.Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity.Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir.Molecular targets for antiviral therapy of cytomegalovirus infections.Differential properties of cytomegalovirus pUL97 kinase isoforms affect viral replication and maribavir susceptibilityThe search for new therapies for human cytomegalovirus infections.The proteome of human cytomegalovirus virions and dense bodies is conserved across different strains.Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins.Cellular p32 recruits cytomegalovirus kinase pUL97 to redistribute the nuclear lamina.The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase DomainCopper-catalyzed annulation of amidines for quinazoline synthesis.Iron-catalyzed cascade reaction of 2-aminobenzyl alcohols with benzylamines: synthesis of quinazolines by trapping of ammonia.Synthesis of quinazolines from 2-aminobenzylamines with benzylamines and N-substituted benzylamines under transition metal-free conditions.One-pot three-component synthesis of quinazolines via a copper-catalysed oxidative amination reaction.Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells.Cuprous Oxide Nanoparticle Supported on Iron Oxide (Cu2 O-Fe3 O4 ): Magnetically Separable and Reusable Nanocatalyst for the Synthesis of Quinazolines
P2860
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P2860
Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Novel chemical class of pUL97 ...... anticytomegaloviral activity.
@en
type
label
Novel chemical class of pUL97 ...... anticytomegaloviral activity.
@en
prefLabel
Novel chemical class of pUL97 ...... anticytomegaloviral activity.
@en
P2093
P2860
P1476
Novel chemical class of pUL97 ...... anticytomegaloviral activity.
@en
P2093
Manfred Marschall
Martina Freitag
Monika Morbitzer
Regina Kupfer
Thomas Herget
P2860
P304
P356
10.1128/AAC.48.11.4154-4162.2004
P407
P577
2004-11-01T00:00:00Z