Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity.
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An Association Map on the Effect of Flavonoids on the Signaling Pathways in Colorectal CancerMyricetin: A Dietary Molecule with Diverse Biological ActivitiesChemoprevention of Breast Cancer by Dietary PolyphenolsMelanocytes as instigators and victims of oxidative stressTrxR1 as a potent regulator of the Nrf2-Keap1 response systemNatural Compounds Modulating Mitochondrial FunctionsIdentification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1Dried whole plant Artemisia annua as an antimalarial therapyTRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress ResponseSelective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl ethyl sulfide in lung epithelial cellsA survey of across-target bioactivity results of small molecules in PubChemIndolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leadsTargeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide.Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver.Methylation of dietary flavones increases their metabolic stability and chemopreventive effectsAcetaminophen reactive intermediates target hepatic thioredoxin reductaseThe anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase.Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assayMyricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo.Hepatocytes lacking thioredoxin reductase 1 have normal replicative potential during development and regeneration.Antibacterial and anti-inflammatory effects of Syzygium jambos L. (Alston) and isolated compounds on acne vulgarisLaser-induced hydrogen radical removal in UV MALDI-MS allows for the differentiation of flavonoid monoglycoside isomers.Quercetin and cancer chemopreventionImmunomodulatory effect of an isolated fraction from Tinospora crispa on intracellular expression of INF-γ, IL-6 and IL-8.Methodological problems with population cancer studies: The forgotten confounding factors.Impact of trivalent arsenicals on selenoprotein synthesisSecondary metabolites constituents and antioxidant, anticancer and antibacterial activities of Etlingera elatior (Jack) R.M.Sm grown in different locations of Malaysia.Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones.Phytochemical constituents and biological activities of different extracts of Strobilanthes crispus (L.) Bremek leaves grown in different locations of Malaysia.Induction of Thioredoxin Reductase 1 by Korean Red Ginseng Water Extract Regulates Cytoprotective Effects on Human Endothelial Cells.Variation in secondary metabolite production as well as antioxidant and antibacterial activities of Zingiber zerumbet (L.) at different stages of growth.Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy.Improving metabolic stability of cancer chemoprotective polyphenols.EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells.Signal transduction and molecular targets of selected flavonoids.Myricetin protects against diet-induced obesity and ameliorates oxidative stress in C57BL/6 mice.Identification of Michael acceptor-centric pharmacophores with substituents that yield strong thioredoxin reductase inhibitory character correlated to antiproliferative activity.APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidaseInhibition of cancer antioxidant defense by natural compounds.
P2860
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P2860
Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Inhibition of Mammalian thiore ...... quercetin anticancer activity.
@en
type
label
Inhibition of Mammalian thiore ...... quercetin anticancer activity.
@en
prefLabel
Inhibition of Mammalian thiore ...... quercetin anticancer activity.
@en
P2093
P50
P1433
P1476
Inhibition of Mammalian thiore ...... quercetin anticancer activity.
@en
P2093
Jianguo Fang
Laura V Papp
Salvador Rodriguez-Nieto
P304
P356
10.1158/0008-5472.CAN-05-3310
P407
P577
2006-04-01T00:00:00Z