Theoretical and practical approaches for prediction of drug-polymer miscibility and solubility.
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Nanoparticle-mediated drug delivery for treating melanomaFundamental aspects of solid dispersion technology for poorly soluble drugsData mining of solubility parameters for computational prediction of drug-excipient miscibility.Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation.Investigation for the amorphous state of ER-34122, a dual 5-lipoxygenase/cyclooxygenase inhibitor with poor aqueous solubility, in HPMC solid dispersion prepared by the solvent evaporation method.Solid-state characterization of Felodipine-Soluplus amorphous solid dispersions.Review: physical chemistry of solid dispersions.Flash nanoprecipitation: prediction and enhancement of particle stability via drug structure.Stability of amorphous pharmaceutical solids: crystal growth mechanisms and effect of polymer additivesInteractions between drugs and polymers influencing hot melt extrusion.Hot-melt extrusion--basic principles and pharmaceutical applications.Refining stability and dissolution rate of amorphous drug formulations.Advances in oral controlled drug delivery: the role of drug-polymer and interpolymer non-covalent interactions.Physical stabilization of low-molecular-weight amorphous drugs in the solid state: a material science approach.Amorphous solid dispersions: a robust platform to address bioavailability challenges.Driving forces for drug loading in drug carriers.Classification of solid dispersions: correlation to (i) stability and solubility (ii) preparation and characterization techniques.Understanding pharmaceutical polymorphic transformations II: crystallization variables and influence on dosage forms.Challenges and Strategies in Thermal Processing of Amorphous Solid Dispersions: A ReviewOptimising Drug Solubilisation in Amorphous Polymer Dispersions: Rational Selection of Hot-melt Extrusion Processing ParametersA New Extrudable Form of Hypromellose: AFFINISOL™ HPMC HME.The role of the carrier in the formulation of pharmaceutical solid dispersions. Part II: amorphous carriers.Rational excipient selection for co-amorphous formulations.Use of the Flory-Huggins theory to predict the solubility of nifedipine and sulfamethoxazole in the triblock, graft copolymer Soluplus.Cationic amphiphilic drugs self-assemble to the core-shell interface of PEGylated phospholipid micelles and stabilize micellar structure.Nano self-assemblies based on cholate grafted poly-L-lysine enhanced the solubility of sterol-like drugs.A systematic approach to design and prepare solid dispersions of poorly water-soluble drug.Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming abilitySpatial characterization of hot melt extruded dispersion systems using thermal atomic force microscopy methods: the effects of processing parameters on phase separation.Leveraging Colloidal Aggregation for Drug-Rich Nanoparticle Formulations.The effects of polymer carrier, hot melt extrusion process and downstream processing parameters on the moisture sorption properties of amorphous solid dispersions.Hot melt extruded amorphous solid dispersion of posaconazole with improved bioavailability: investigating drug-polymer miscibility with advanced characterisation.Molecular modeling of temperature dependence of solubility parameters for amorphous polymers.Investigation of the in vitro performance difference of drug-Soluplus® and drug-PEG 6000 dispersions when prepared using spray drying or lyophilization.Construction and Validation of Binary Phase Diagram for Amorphous Solid Dispersion Using Flory-Huggins TheoryThe influence of drug physical state on the dissolution enhancement of solid dispersions prepared via hot-melt extrusion: a case study using olanzapine.Development of valsartan-loaded gelatin microcapsule without crystal change using hydroxypropylmethylcellulose as a stabilizer.Screening methodologies for the development of spray-dried amorphous solid dispersions.Porous aerosil loading probucol using supercritical carbon dioxide: preparation, in vitro and in vivo characteristics.Theoretical prediction of a phase diagram for solid dispersions.
P2860
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P2860
Theoretical and practical approaches for prediction of drug-polymer miscibility and solubility.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Theoretical and practical appr ...... er miscibility and solubility.
@en
type
label
Theoretical and practical appr ...... er miscibility and solubility.
@en
prefLabel
Theoretical and practical appr ...... er miscibility and solubility.
@en
P1476
Theoretical and practical appr ...... mer miscibility and solubility
@en
P2093
Patrick J Marsac
Sheri L Shamblin
P304
P356
10.1007/S11095-006-9063-9
P577
2006-08-24T00:00:00Z