Apical sorting of ADAMTS13 in vascular endothelial cells and Madin-Darby canine kidney cells depends on the CUB domains and their association with lipid rafts.
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Pathophysiology of thrombotic thrombocytopenic purpuraPathogenesis of thrombotic microangiopathiesProteolytic processing of von Willebrand factor by adamts13 and leukocyte proteasesADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpuraInflammatory cytokines inhibit ADAMTS13 synthesis in hepatic stellate cells and endothelial cellsHepatic stellate cell damage may lead to decreased plasma ADAMTS13 activity in ratsFurther characterization of ADAMTS-13 inactivation by thrombin.ADAMTS13 phenotype in plasma from normal individuals and patients with thrombotic thrombocytopenic purpuraAn IAP retrotransposon in the mouse ADAMTS13 gene creates ADAMTS13 variant proteins that are less effective in cleaving von Willebrand factor multimers.Podocytes express ADAMTS13 in normal renal cortex and in patients with thrombotic thrombocytopenic purpura.Correction of ADAMTS13 deficiency by in utero gene transfer of lentiviral vector encoding ADAMTS13 genes.Effects of naturally occurring mutations in CUB-1 domain on synthesis, stability, and activity of ADAMTS-13.Correction of murine ADAMTS13 deficiency by hematopoietic progenitor cell-mediated gene therapyMechanisms of microvascular thrombosis in thrombotic thrombocytopenic purpura.A shear-based assay for assessing plasma ADAMTS13 activity and inhibitors in patients with thrombotic thrombocytopenic purpuraA high LDH to AST ratio helps to differentiate pregnancy-associated thrombotic thrombocytopenic purpura (TTP) from HELLP syndrome.Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models.ADAMTS13 and von Willebrand factor interactions.Phenotypic expression of ADAMTS13 in glomerular endothelial cellsDetection of a secreted metalloprotease within the nuclei of liver cellsIncreased expressions of ADAMTS-13, neuronal nitric oxide synthase, and neurofilament correlate with severity of neuropathology in Border disease virus-infected small ruminants.The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow.Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney.Structure-function and regulation of ADAMTS-13 protease.N-Glycans of ADAMTS13 modulate its secretion and von Willebrand factor cleaving activity.The role of membrane microdomains in transmembrane signaling through the epithelial glycoprotein Gp140/CDCP1.Role of fluid shear stress in regulating VWF structure, function and related blood disorders.ADAMTS13: more than a regulator of thrombosis.IL-1β down-regulates ADAMTS-13 mRNA expression in cells of the central nervous system.Increased expressions of ADAMTS-13 and apoptosis contribute to neuropathology during Toxoplasma gondii encephalitis in mice.von Willebrand factor multimerization and the polarity of secretory pathways in endothelial cells.ADAMTS13 and Von Willebrand factor in patients undergoing hemodialysis.Expression of ADAMTS13 in Normal and Abnormal Placentae and Its Potential Role in Angiogenesis and Placenta Development.Markers and Biomarkers of Endothelium: When Something Is Rotten in the State.From humoral rejection to generalized thrombotic microangiopathy--role of acquired ADAMTS13 deficiency in a renal allograft recipient.A splice variant of ADAMTS13 is expressed in human hepatic stellate cells and cancerous tissues.Cysteine residues in CUB-1 domain are critical for ADAMTS13 secretion and stability.Protein Z and protein Z-dependent protease inhibitor and renal tubules.ADAMTS13 activity to antigen ratio in physiological and pathological conditions associated with an increased risk of thrombosis
P2860
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P2860
Apical sorting of ADAMTS13 in vascular endothelial cells and Madin-Darby canine kidney cells depends on the CUB domains and their association with lipid rafts.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Apical sorting of ADAMTS13 in ...... association with lipid rafts.
@en
type
label
Apical sorting of ADAMTS13 in ...... association with lipid rafts.
@en
prefLabel
Apical sorting of ADAMTS13 in ...... association with lipid rafts.
@en
P2093
P2860
P1433
P1476
Apical sorting of ADAMTS13 in ...... association with lipid rafts.
@en
P2093
Dezhi Shang
Masami Niiya
X Long Zheng
X Wu Zheng
P2860
P304
P356
10.1182/BLOOD-2006-02-002139
P407
P577
2006-04-04T00:00:00Z