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Influence of key residues on the heterologous extracellular production of fungal ribonuclease U2 in the yeast Pichia pastoris.Cleavage of the sarcin-ricin loop of 23S rRNA differentially affects EF-G and EF-Tu bindingFungal ribotoxins: Natural protein-based weapons against insects.Involvement of the amino-terminal beta-hairpin of the Aspergillus ribotoxins on the interaction with membranes and nonspecific ribonuclease activity.Involvement of loops 2 and 3 of α-sarcin on its ribotoxic activity.Hirsutellin A: A Paradigmatic Example of the Insecticidal Function of Fungal Ribotoxins.Fungal Ribotoxins: A Review of Potential Biotechnological Applications.A non-cytotoxic but ribonucleolytically specific ribotoxin variant: implication of tryptophan residues in the cytotoxicity of hirsutellin A.Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity.Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding.Leucine 145 of the ribotoxin alpha-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein.Characterization of a new toxin from the entomopathogenic fungus Metarhizium anisopliae: the ribotoxin anisoplin.Fungal extracellular ribotoxins as insecticidal agents.NMR structure of the noncytotoxic alpha-sarcin mutant Delta(7-22): the importance of the native conformation of peripheral loops for activity.The behavior of sea anemone actinoporins at the water-membrane interface.Precise alignment of peptidyl tRNA by the decoding center is essential for EF-G-dependent translocation.Conserved asparagine residue 54 of alpha-sarcin plays a role in protein stability and enzyme activity.Anomalous electrophoretic behavior of a very acidic protein: ribonuclease U2.Minimized natural versions of fungal ribotoxins show improved active site plasticity.The acidic ribosomal stalk proteins are not required for the highly specific inactivation exerted by α-sarcin of the eukaryotic ribosome.Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.Implication of an Asp residue in the ribonucleolytic activity of hirsutellin A reveals new electrostatic interactions at the active site of ribotoxinsProduction and characterization of scFvA33T1, an immunoRNase targeting colon cancer cellsRibonuclease U2: cloning, production inPichia pastorisand affinity chromatography purification of the active recombinant proteinThe ribonucleolytic activity of the ribotoxin α-sarcin is not essential for in vitro protein biosynthesis inhibitionModeling the highly specific ribotoxin recognition of ribosomesThe solubility of the ribotoxin alpha-sarcin, produced as a recombinant protein in Escherichia coli, is increased in the presence of thioredoxinRNase U2 and alpha-sarcin: a study of relationshipsStructural and enzymatic properties of Ageritin, a novel metal-dependent ribotoxin-like protein with antitumor activityBinding and enzymatic properties of Ageritin, a fungal ribotoxin with novel zinc-dependent function
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Lucía García-Ortega
@ast
Lucía García-Ortega
@en
Lucía García-Ortega
@es
Lucía García-Ortega
@nl
Lucía García-Ortega
@sl
type
label
Lucía García-Ortega
@ast
Lucía García-Ortega
@en
Lucía García-Ortega
@es
Lucía García-Ortega
@nl
Lucía García-Ortega
@sl
prefLabel
Lucía García-Ortega
@ast
Lucía García-Ortega
@en
Lucía García-Ortega
@es
Lucía García-Ortega
@nl
Lucía García-Ortega
@sl
P1053
J-3278-2016
P106
P21
P31
P3829
P496
0000-0003-3479-2213