Immortalization of primary epithelial cells requires first- and second-exon functions of adenovirus type 5 12S.
about
Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformationA region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasisPhysical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3CExpression of the pRb-binding regions of E1A enables efficient transformation of primary epithelial cells by v-src.Domains of E1A that bind p105Rb, p130, and p300 are required to block nerve growth factor-induced neurite growth in PC12 cells.Interaction of MEQ protein and C-terminal-binding protein is critical for induction of lymphomas by Marek's disease virus.Opposing oncogenic activities of small DNA tumor virus transforming proteins.Efficient nuclear localization and immortalizing ability, two functions dependent on the adenovirus type 5 (Ad5) E1A second exon, are necessary for cotransformation with Ad5 E1B but not with T24rasRole of p300-family proteins in E1A oncogene induction of cytolytic susceptibility and tumor cell rejectionThe adenovirus E1A 12S product displays functional redundancy in activating the human proliferating cell nuclear antigen promoterInduction of gene expression by exon 2 of the major E1A proteins of adenovirus type 5.Interaction of CtBP with adenovirus E1A suppresses immortalization of primary epithelial cells and enhances virus replication during productive infection.Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors.The Influence of E1A C-Terminus on Adenovirus Replicative Cycle.
P2860
Q24303599-719D517A-E049-4368-810A-9CB669020079Q24321630-5681FFA9-1DAF-404D-859B-035620E69B64Q33292390-42A1BFF1-6120-41F8-BAB7-932A614E5687Q33783051-D78E050C-B287-4A86-9B99-0BA0C3F8DF2AQ34436312-721AB1C9-DBDF-4698-8665-FCBF1D6888F1Q34478563-403A1FD3-8E6F-4FFC-BCAA-3037A686016BQ34985200-CFAAAEC7-8BFC-4C22-B96B-21F574D6CD24Q35852705-8CFA3A47-1636-441F-B0F1-02B4551855F7Q35940369-D3DF5B94-0A38-4ED9-991D-509DAF427434Q36640126-A0F17FC7-40D7-4420-B9BC-DA675737D503Q36654791-F8EBAC2D-890E-46E8-B84E-189B3FB6770DQ37066498-A11B9032-27EA-4D0B-BC35-5A3F1DDF646CQ41859522-07BCE2D0-18BA-44F6-82F7-27C7E3313C20Q47108249-50730A4B-83A8-4AB1-B2AC-67D9391B1C1B
P2860
Immortalization of primary epithelial cells requires first- and second-exon functions of adenovirus type 5 12S.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Immortalization of primary epi ...... ions of adenovirus type 5 12S.
@en
type
label
Immortalization of primary epi ...... ions of adenovirus type 5 12S.
@en
prefLabel
Immortalization of primary epi ...... ions of adenovirus type 5 12S.
@en
P2860
P1433
P1476
Immortalization of primary epi ...... ions of adenovirus type 5 12S.
@en
P2093
Douglas JL
Quinlan MP
P2860
P304
P407
P577
1992-04-01T00:00:00Z