A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin.
about
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) ProdrugsInsights into the acid-base properties of Pt(IV)-diazidodiam(m)inedihyroxido complexes from multinuclear NMR spectroscopy.Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: a light-activated antitumor platinum complex that kills human cancer cells by an apoptosis-independent mechanism.Photocytotoxic trans-diam(m)ine platinum(IV) diazido complexes more potent than their cis isomers.Photodynamic killing of cancer cells by a Platinum(II) complex with cyclometallating ligand.A potent cytotoxic photoactivated platinum complexNew trends for metal complexes with anticancer activityNovel metals and metal complexes as platforms for cancer therapyCurrent applications and future potential for bioinorganic chemistry in the development of anticancer drugs.Keys for unlocking photolabile metal-containing cages.Tuning heavy metal compounds for anti-tumor activity: is diversity the key to ruthenium's success?Effects of light-activated diazido-PtIV complexes on cancer cells in vitro.Binding of an organo-osmium(II) anticancer complex to guanine and cytosine on DNA revealed by electron-based dissociations in high resolution Top-Down FT-ICR mass spectrometry.Target-selective delivery and activation of platinum-based anticancer agents.Studies on Photocleavage, DNA Binding, Cytotoxicity, and Docking Studies of Ruthenium(II) Mixed Ligand Complexes.Platinum complexes as light promoted anticancer agents: a redefined strategy for controlled activation.Metal Complexes for Two-Photon Photodynamic Therapy: A Cyclometallated Iridium Complex Induces Two-Photon Photosensitization of Cancer Cells under Near-IR Light.Delivering a photosensitive transplatin prodrug to overcome cisplatin drug resistance.Cellular accumulation, lipophilicity and photocytotoxicity of diazido platinum(IV) anticancer complexes.Zinc(II) complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers that trigger DNA damage-mediated p53 phosphorylation in cancer cells.Studies on the photoactivation of two cytotoxic trans,trans,trans-diazidodiaminodihydroxo-Pt(IV) complexes.Photoinduced reactions of cis,trans,cis-[Pt(IV)(N3)2(OH)2(NH3)2) with 1-methylimidazole.Photoactivation of trans diamine platinum complexes in aqueous solution and effect on reactivity towards nucleotides.Synthesis, characterisation and photochemistry of Pt(IV) pyridyl azido acetato complexes.Controlling Platinum, Ruthenium and Osmium Reactivity for Anticancer Drug Design.Advances in platinum chemotherapeutics.Probing platinum azido complexes by 14N and 15N NMR spectroscopy.Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA.Unprecedented carbon-carbon bond formation induced by photoactivation of a platinum(IV)-diazido complex.Combination of Ru(ii) complexes and light: new frontiers in cancer therapy.A computational approach to tuning the photochemistry of platinum(IV) anticancer agents.Primary photochemical processes for Pt(iv) diazido complexes prospective in photodynamic therapy of tumors.Exploring the boundaries of direct detection and characterization of labile isomers - a case study of copper(ii)-dipeptide systems.Ground and excited state properties of photoactive platinum(IV) diazido complexes: theoretical considerations.Mechanistic Understanding of the Divergent Cyclizations of o-Alkynylbenzaldehyde Acetals and Thioacetals Catalyzed by Metal Halides.Substituent effect and wavelength dependence of the photoinduced Ru-O homolysis in the [Ru(bpy)2(py-SO3)](+)-type complexes.Activating platinum anticancer complexes with visible light.Oxygen and Pt(II) self-generating conjugate for synergistic photo-chemo therapy of hypoxic tumor.Sequence-dependent attack on peptides by photoactivated platinum anticancer complexes.
P2860
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P2860
A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin.
@en
type
label
A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin.
@en
prefLabel
A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin.
@en
P2093
P356
P1476
A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin.
@en
P2093
Alice Dawson
Fiona S Mackay
Harry Moseley
James Ferguson
Julie A Woods
Peter J Sadler
Simon Parsons
P304
P356
10.1002/CHEM.200501601
P407
P577
2006-04-01T00:00:00Z