Proliferating human cells hypomorphic for origin recognition complex 2 and pre-replicative complex formation have a defect in p53 activation and Cdk2 kinase activation.
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Replication licensing and cancer--a fatal entanglement?DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1Global regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation.Replication licensing promotes cyclin D1 expression and G1 progression in untransformed human cells.CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S Phase to Mitosis.Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligaseThe Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2Behavior of replication origins in Eukaryota - spatio-temporal dynamics of licensing and firingDivergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival.Dormant origins, the licensing checkpoint, and the response to replicative stressesFlipping the switch from g1 to s phase with e3 ubiquitin ligasesThe contribution of dormant origins to genome stability: from cell biology to human genetics.The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines.Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome.The licensing checkpoint opens up.Rapid DNA replication origin licensing protects stem cell pluripotency.The Temporal Regulation of S Phase Proteins During G1.Lgr5+ intestinal stem cells reside in an unlicensed G1 phase.Depletion of the pre‐RC proteins induces Chk1/Chk2 independent checkpoint responses and apoptotic cell death in HeLa cells
P2860
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P2860
Proliferating human cells hypomorphic for origin recognition complex 2 and pre-replicative complex formation have a defect in p53 activation and Cdk2 kinase activation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Proliferating human cells hypo ...... on and Cdk2 kinase activation.
@en
type
label
Proliferating human cells hypo ...... on and Cdk2 kinase activation.
@en
prefLabel
Proliferating human cells hypo ...... on and Cdk2 kinase activation.
@en
P2093
P2860
P50
P356
P1476
Proliferating human cells hypo ...... ion and Cdk2 kinase activation
@en
P2093
Helene Labit
Kathrin Marheineke
Maria Zannis-Hadjopoulos
Olivia Novac
Yuichi J Machida
P2860
P304
P356
10.1074/JBC.M507150200
P407
P577
2006-01-10T00:00:00Z