Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives.
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Biologic complexity in sickle cell disease: implications for developing targeted therapeuticsDrugs for preventing red blood cell dehydration in people with sickle cell diseaseMagnesium for treating sickle cell diseaseDrugs for preventing red blood cell dehydration in people with sickle cell diseaseDrugs for preventing red blood cell dehydration in people with sickle cell diseaseA human intermediate conductance calcium-activated potassium channelTriggers, inhibitors, mechanisms, and significance of eryptosis: the suicidal erythrocyte death2015 Clinical trials update in sickle cell anemiaStimulation of suicidal erythrocyte death by lipoxygenase inhibitor Bay-Y5884Bradykinin attenuates the [Ca(2+)](i) response to angiotensin II of renal juxtamedullary efferent arterioles via an EDHFClotrimazole analogues: effective blockers of the slow afterhyperpolarization in cultured rat hippocampal pyramidal neuronesIn silico repositioning-chemogenomics strategy identifies new drugs with potential activity against multiple life stages of Schistosoma mansoniMagnesium for treating sickle cell diseaseBeneficial effect of aurothiomalate on murine malaria.Oral magnesium pidolate: effects of long-term administration in patients with sickle cell disease.Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease.Stimulation of suicidal erythrocyte death by fumagillin.PTPepsilon has a critical role in signaling transduction pathways and phosphoprotein network topology in red cells.Basolateral potassium (IKCa) channel inhibition prevents increased colonic permeability induced by chemical hypoxia.Solenostemon monostachyus, Ipomoea involucrata and Carica papaya seed oil versus Glutathione, or Vernonia amygdalina: methanolic extracts of novel plants for the management of sickle cell anemia disease.Adhesion of annexin 7 deficient erythrocytes to endothelial cellsDeveloping treatment for sickle cell disease.Anti-malarial effect of gum arabic.Prevention of red cell dehydration: a possible new treatment for sickle cell disease.Enhanced suicidal erythrocyte death in mice carrying a loss-of-function mutation of the adenomatous polyposis coli geneTrpc2 depletion protects red blood cells from oxidative stress-induced hemolysis.Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery.Therapeutic potential of KCa3.1 blockers: recent advances and promising trends.Ion transport pathology in the mechanism of sickle cell dehydration.Trafficking of intermediate (KCa3.1) and small (KCa2.x) conductance, Ca(2+)-activated K(+) channels: a novel target for medicinal chemistry efforts?N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytesPotent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum.Azathioprine favourably influences the course of malaria.Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease.The antifungal antibiotic, clotrimazole, inhibits Cl- secretion by polarized monolayers of human colonic epithelial cells.Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell diseaseThe antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera.Triggering of suicidal erythrocyte death by penta-O-galloyl-β-D-glucose.Role of ion transport in control of apoptotic cell death.Ceramide in the regulation of eryptosis, the suicidal erythrocyte death.
P2860
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P2860
Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Inhibition of Ca(2+)-dependent ...... d other imidazole derivatives.
@en
type
label
Inhibition of Ca(2+)-dependent ...... d other imidazole derivatives.
@en
prefLabel
Inhibition of Ca(2+)-dependent ...... d other imidazole derivatives.
@en
P2093
P2860
P356
P1476
Inhibition of Ca(2+)-dependent ...... d other imidazole derivatives.
@en
P2093
Brugnara C
de Franceschi L
P2860
P304
P356
10.1172/JCI116597
P407
P577
1993-07-01T00:00:00Z