about
Peculiar features in the crystal structure of the adduct formed between cis-PtI2(NH3)2 and hen egg white lysozymeInteractions between anticancer trans-platinum compounds and proteins: crystal structures and ESI-MS spectra of two protein adducts of trans-(dimethylamino)(methylamino)dichloridoplatinum(II)Influence of amine ligands on the aquation and cytotoxicity of trans-diamine platinum(II) anticancer complexes.Solution behaviour and biomolecular interactions of two cytotoxic trans-platinum(II) complexes bearing aliphatic amine ligands.Proteins as possible targets for cytotoxic trans-platinum(II) complexes with aliphatic amine ligands: Further exceptions to the DNA paradigm.Non-classical structures among current platinum complexes with potential as antitumor drugs.Synthesis, cytotoxic activities and proposed mode of binding of a series of bis([(9-oxo-9,10-dihydroacridine-4-carbonyl)amino]alkyl) alkylamines.Reactivity and biological properties of a series of cytotoxic PtI2(amine)2 complexes, either cis or trans configured.Increasing DNA reactivity and in vitro antitumor activity of trans diiodido Pt(II) complexes with UVA light.cis-Pt I2(NH3)2: a reappraisal.Design and biological evaluation of new platinum(II) complexes bearing ligands with DNA-targeting ability.Synthesis, cytotoxicity, DNA interaction and cell cycle studies of trans-diiodophosphine Pt(II) complexes.The second generation of iodido complexes: trans-[PtI2(amine)(amine')] bearing different aliphatic amines.Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II) Complex.Oxidation of anticancer Pt(II) complexes with monodentate phosphane ligands: towards stable but active Pt(IV) prodrugs.An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug.The preparation and characterization of trans-platinum(IV) complexes with unusually high cytotoxicity.The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine.Inhibition of p38-MAPK potentiates cisplatin-induced apoptosis via GSH depletion and increases intracellular drug accumulation in growth-arrested kidney tubular epithelial cells.Influence of (hydroxymethyl)pyridine and pyridine-carboxylic acids, in trans-position to the isopropylamine and amine ligands, on the cytotoxicity of platinum complexes.New trans-platinum drugs with phosphines and amines as carrier ligands induce apoptosis in tumor cells resistant to cisplatin.Trans platinum complexes design: one novel water soluble oxime derivative that contains aliphatic amines in trans configuration.Structural characterization, DNA interactions, and cytotoxicity of new transplatin analogues containing one aliphatic and one planar heterocyclic amine ligand.Novel transplatinum(II) complexes with [N2O2] donor sets. Cellular pharmacology and apoptosis induction in Pam 212-ras cells.Photoactivation of trans diamine platinum complexes in aqueous solution and effect on reactivity towards nucleotides.Conjugation of testosterone modifies the interaction of mono-functional cationic platinum(II) complexes with DNA, causing significant alterations to the DNA helix.Enhanced Cytotoxicity and Reactivity of a Novel Platinum(IV) Family with DNA-Targeting Naphthalimide Ligands.Combining imaging and anticancer properties with new heterobimetallic Pt(ii)/M(i) (M = Re, 99mTc) complexes.Reactions of a tetranuclear Pt-thiosemicarbazone complex with model proteins.Using phosphine ligands with a biological role to modulate reactivity in novel platinum complexes.Cisplatin and its dibromido analogue: a comparison of chemical and biological profiles.XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer CellsNonconventionaltrans-Platinum Complexes Functionalized with RDG Peptides: Chemical and Cytototoxicity StudiesIsolation of an Intermediate in the Platination ofp-Nitroacetophenone 4-Methylthiosemicarbazone: Potential Application as an Antitumor DrugPlatinum(IV) Complexes of 3- and 4-Picolinic Acids Containing Ammine or Isopropylamine Ligands - Synthesis, Characterization, X-ray Structures, and Evaluation of Their Cytotoxic Activity against Cancer Cell Lines[1H,15N] NMR studies of the aquation of cis-diamine platinum(II) complexesContribution to the SAR field of metallated and coordination complexesPalladated and platinated complexes derived from phenylacetaldehyde thiosemicarbazone with cytotoxic activity in cis-DDP resistant tumor cells. Formation of DNA interstrand cross-links by these complexesVersatile Route to trans-Platinum(II) Complexes via Manipulation of a Coordinated 3-(Pyridin-3-yl)propanoic Acid LigandFour-component relativistic 31P NMR calculations for trans-platinum(ii) complexes: importance of the solvent and dynamics in spectral simulations.
P50
Q27687615-18993B06-445A-467E-8D49-66A8488B2FDDQ27694548-A79D74AC-DB1A-46FE-B253-F187CC9E7541Q33432865-FCD337BE-FAEB-4070-AE56-EE6CDE8FDCEBQ33490676-C4175BFE-762D-455E-B47C-BF6A4287B8F6Q37576021-7C7947C0-DDFA-4FE0-8D12-6BE710CAC407Q37951062-E666A8E2-6A44-4747-9B02-BEEFDA5A8B22Q38290063-2D009DA1-BF43-4EE2-8324-66DC73A23EC2Q38328964-6E86A692-468B-491B-BEB4-872F07A9ADE4Q38841945-22E844DF-037B-4766-8AEC-DA3991B7D8EAQ38847816-6B6D447F-D21F-4838-B939-DC4A5F4C5FB4Q38939982-A2295750-FCB1-4D90-BB47-AB66BC95C790Q38948395-75371D1C-933E-40E9-8B97-EE84DABF446DQ39149641-88586DCB-F8C0-4236-A80B-8B1B4E08DD5AQ39155790-D7171461-E02E-496C-A38C-6E883AE7A0EBQ39165275-846903A2-64BF-4DAC-AD49-0527329CA983Q39638588-77BBEEDE-D2DD-4EA3-9D65-47A62E8F8B81Q39645952-3FF79677-4616-46E5-90AA-B444B3622740Q39783936-06DFBA4A-00A1-4E0C-8E23-7B48EA5064B2Q39829228-96C212B9-06A1-4CBB-84E8-1224829A221FQ39923505-329B87D7-8136-4A91-9047-B938799E21BAQ40149878-8024C4E1-E94B-4777-BF69-52E3332230ACQ40218512-D2AFFD06-F179-4A16-9E25-A30FD2798988Q40293345-03213CD0-4082-4CC6-9BFA-817545EAB7FFQ40334077-19C477C9-9105-486E-AC6E-BEDB90D099A3Q42127911-985A6ED0-F174-41FE-819C-1BA75BED5F3CQ42843985-912CFBD1-C5C6-425F-BA2A-941EFA4FAC5EQ46368472-8F0FA1AB-003E-4878-817D-DFAA117B60FFQ48843560-16B76144-362D-4438-9883-E57E3A5B37E3Q49901016-CCBDCA34-E9AC-4110-95AC-829A49DB833BQ52363628-9C3BE2A4-6614-4286-8527-BD38AE541AE2Q52874614-986036B1-524E-4C1C-A3B5-1F12362F51A1Q58606469-141BAFD4-7D2D-499A-81AA-4744E55E23A3Q60220358-89CE2413-DC84-4961-803E-E4AFDFE9027FQ60584724-158718A0-0B28-4AF9-AAB5-BCC1D800AE8BQ60584725-35B1D4E3-B44D-41F7-A128-624FE726BBC2Q60626589-98861B88-F3BD-47B5-8E12-E0621D52B7D7Q60626617-EC7474C7-EB93-40CD-B138-8F9BA21D12C5Q60626661-4919E365-1095-451A-92CD-C1DB7B9B4FFCQ63982364-1E2E6664-A747-4297-AA78-142DB9D4BA9DQ63982368-E464973C-7F4F-4834-9E46-9C65D6F32010
P50
description
hulumtuese
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Adoración G. Quiroga
@ast
Adoración G. Quiroga
@en
Adoración G. Quiroga
@es
Adoración G. Quiroga
@nl
type
label
Adoración G. Quiroga
@ast
Adoración G. Quiroga
@en
Adoración G. Quiroga
@es
Adoración G. Quiroga
@nl
prefLabel
Adoración G. Quiroga
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Adoración G. Quiroga
@en
Adoración G. Quiroga
@es
Adoración G. Quiroga
@nl
P1053
D-4512-2013
P106
P1153
6603944369
P21
P2798
P31
P3829
P496
0000-0002-9261-9542