A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and tumor necrosis factor-mediated NF-kappa B activation.

A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and tumor necrosis factor-mediated NF-kappa B activation.

Item
http://www.wikidata.org/entity/Q40335919
Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347Structural Basis for Recognition of Diubiquitins by NEMONew mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein.Dento-craniofacial phenotypes and underlying molecular mechanisms in hypohidrotic ectodermal dysplasia (HED): a review.Rare mendelian primary immunodeficiency diseases associated with impaired NF-κB signalingEDA-ID and IP, two faces of the same coin: how the same IKBKG/NEMO mutation affecting the NF-κB pathway can cause immunodeficiency and/or inflammation.The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-κB by merkel polyomavirus small tumour antigen.The zinc finger of NEMO is a functional ubiquitin-binding domain.Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome.Alterations of the IKBKG locus and diseases: an update and a report of 13 novel mutations.Evidence for M1-Linked Polyubiquitin-Mediated Conformational Change in NEMO.Decreased expression in nuclear factor-κB essential modulator due to a novel splice-site mutation causes X-linked ectodermal dysplasia with immunodeficiency.
P2860

A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and tumor necrosis factor-mediated NF-kappa B activation.

Item
http://www.wikidata.org/entity/Q40335919
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
A point mutation in NEMO assoc ...... ediated NF-kappa B activation.
@en
type
label
A point mutation in NEMO assoc ...... ediated NF-kappa B activation.
@en
prefLabel
A point mutation in NEMO assoc ...... ediated NF-kappa B activation.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
A point mutation in NEMO assoc ...... ediated NF-kappa B activation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921