6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta.
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A specific fluorescent probe reveals compromised activity of methionine sulfoxide reductases in Parkinson's disease.Tyrosine Hydroxylase Binding to Phospholipid Membranes Prompts Its Amyloid Aggregation and Compromises Bilayer Integrity.The Parkinsonian mimetic, 6-OHDA, impairs axonal transport in dopaminergic axons.Bilateral six-hydroxydopamine administration to PFC prevents the expression of behavioral sensitization to methylphenidate.Adaptation to chronic MG132 reduces oxidative toxicity by a CuZnSOD-dependent mechanismEnhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells.Dissociation of progressive dopaminergic neuronal death and behavioral impairments by Bax deletion in a mouse model of Parkinson's diseases1-Benzyl-1,2,3,4-tetrahydroisoquinoline, an endogenous neurotoxic compound, disturbs the behavioral and biochemical effects of L-DOPA: in vivo and ex vivo studies in the rat.Alterations in energy/redox metabolism induced by mitochondrial and environmental toxins: a specific role for glucose-6-phosphate-dehydrogenase and the pentose phosphate pathway in paraquat toxicityHuman albumin prevents 6-hydroxydopamine-induced loss of tyrosine hydroxylase in in vitro and in vivo.Striatal molecular signature of subchronic subthalamic nucleus high frequency stimulation in parkinsonian rat.Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson diseasePeroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade.Activation of GSK-3β and caspase-3 occurs in Nigral dopamine neurons during the development of apoptosis activated by a striatal injection of 6-hydroxydopamineConcentration-dependent opposite effects of 1-benzyl-1,2,3,4-tetrahydroisoquinoline on markers of apoptosis: in vitro and ex vivo studies.San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells.Protein kinase D1 (PKD1) phosphorylation promotes dopaminergic neuronal survival during 6-OHDA-induced oxidative stress.Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's diseaseAndrogens exacerbate motor asymmetry in male rats with unilateral 6-hydroxydopamine lesion.Formation of dopamine adducts derived from brain polyunsaturated fatty acids: mechanism for Parkinson diseaseModeling mitochondrial dysfunctions in the brain: from mice to men.6-Hydroxydopamine induces mitochondrial ERK activation.Major Alterations of Phosphatidylcholine and Lysophosphotidylcholine Lipids in the Substantia Nigra Using an Early Stage Model of Parkinson's Disease.Neuronal effects of 4-t-Butylcatechol: a model for catechol-containing antioxidantsProaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons.Inhibition of the Fe(III)-catalyzed dopamine oxidation by ATP and its relevance to oxidative stress in Parkinson's diseaseOxidative stress defines the neuroprotective or neurotoxic properties of androgens in immortalized female rat dopaminergic neuronal cells.Targeting the progression of Parkinson's disease.Androgens induce dopaminergic neurotoxicity via caspase-3-dependent activation of protein kinase Cdelta.α-Tocopherol at Nanomolar Concentration Protects Cortical Neurons against Oxidative Stress.Silymarin improved 6-OHDA-induced motor impairment in hemi-parkisonian rats: behavioral and molecular studyThe contributions of antioxidant activity of lipoic acid in reducing neurogenerative progression of Parkinson's disease: a review.Chromaffin cells as a model to evaluate mechanisms of cell death and neuroprotective compounds.Agmatine Protects Against 6-OHDA-Induced Apoptosis, and ERK and Akt/GSK Disruption in SH-SY5Y Cells.Cell death caused by the synergistic effects of zinc and dopamine is mediated by a stress sensor gene Gadd45b - implication in the pathogenesis of Parkinson's disease.BAG1 is neuroprotective in in vivo and in vitro models of Parkinson's disease.RA Differentiation Enhances Dopaminergic Features, Changes Redox Parameters, and Increases Dopamine Transporter Dependency in 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells.Neuroprotective potentials of neurotrophin rich olfactory ensheathing cell's conditioned media against 6OHDA-induced oxidative damage.The novel tetramethylpyrazine bis-nitrone (TN-2) protects against MPTP/MPP+-induced neurotoxicity via inhibition of mitochondrial-dependent apoptosis.Protein kinase C delta mediated cytotoxicity of 6-Hydroxydopamine via sustained extracellular signal-regulated kinase 1/2 activation in PC12 cells.
P2860
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P2860
6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
6-hydroxydopamine-induced apop ...... tion of protein kinase Cdelta.
@en
type
label
6-hydroxydopamine-induced apop ...... tion of protein kinase Cdelta.
@en
prefLabel
6-hydroxydopamine-induced apop ...... tion of protein kinase Cdelta.
@en
P2093
P2860
P356
P1476
6-hydroxydopamine-induced apop ...... tion of protein kinase Cdelta.
@en
P2093
Katharine Hanrott
Louise Gudmunsen
Michael J O'Neill
Susan Wonnacott
P2860
P304
P356
10.1074/JBC.M511560200
P407
P577
2005-12-16T00:00:00Z