RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferation.
about
Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatmentRegulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cellsCholine Metabolism Alteration: A Focus on Ovarian CancerCholine metabolism-based molecular diagnosis of cancer: an updateKey Players in Choline Metabolic Reprograming in Triple-Negative Breast CancerCholine kinase and its functionHighly specific antibodies for co-detection of human choline kinase α1 and α2 isoformsOmeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cellsDownregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer CellsSilencing of the glycerophosphocholine phosphodiesterase GDPD5 alters the phospholipid metabolite profile in a breast cancer model in vivo as monitored by (31) P MRS.A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products.Non-invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism.Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism.Phospholipase D1 and choline kinase-α are interactive targets in breast cancer.Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells.Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models.PSMA-targeted theranostic nanoplex for prostate cancer therapy.Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using 1H-nuclear magnetic resonance spectroscopy.Molecular Effects of Doxorubicin on Choline Metabolism in Breast Cancer.Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer1H/31P polarization transfer at 9.4 Tesla for improved specificity of detecting phosphomonoesters and phosphodiesters in breast tumor models.A hyperpolarized choline molecular probe for monitoring acetylcholine synthesis.Applications of molecular MRI and optical imaging in cancer.A critical role for choline kinase-alpha in the aggressiveness of bladder carcinomasGlycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancerCharacterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway.Understanding cancer-induced cachexia: imaging the flame and its fuel.Inhibition of phosphatidylcholine-specific phospholipase C results in loss of mesenchymal traits in metastatic breast cancer cells.Nanoplex delivery of siRNA and prodrug enzyme for multimodality image-guided molecular pathway targeted cancer therapyDirect inhibition of choline kinase by a near-infrared fluorescent carbocyanineIdentification of potential synthetic lethal genes to p53 using a computational biology approachCholine kinase overexpression increases invasiveness and drug resistance of human breast cancer cellsThe metabolic responses to hepatitis B virus infection shed new light on pathogenesis and targets for treatment.A novel small molecule antagonist of choline kinase-α that simultaneously suppresses MAPK and PI3K/AKT signalingNoninvasive imaging identifies new roles for cyclooxygenase-2 in choline and lipid metabolism of human breast cancer cellsCholine metabolism in malignant transformation.Development of radiotracers for oncology--the interface with pharmacologyMetabolic tumor imaging using magnetic resonance spectroscopy.Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinomaModeling cancer metabolism on a genome scale.
P2860
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P2860
RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
RNA interference-mediated chol ...... ion and reduces proliferation.
@en
type
label
RNA interference-mediated chol ...... ion and reduces proliferation.
@en
prefLabel
RNA interference-mediated chol ...... ion and reduces proliferation.
@en
P2093
P1433
P1476
RNA interference-mediated chol ...... ion and reduces proliferation.
@en
P2093
Kristine Glunde
Noriko Mori
Venu Raman
Zaver M Bhujwalla
P304
11034-11043
P356
10.1158/0008-5472.CAN-05-1807
P407
P577
2005-12-01T00:00:00Z