A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma.
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Sox11 is expressed in early progenitor human multipotent stromal cells and decreases with extensive expansion of the cellsRole of osteocytes in multiple myeloma bone diseaseTgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growthZoledronic acid preserves bone structure and increases survival but does not limit tumour incidence in a prostate cancer bone metastasis modelRoles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation associated with oral cancers: significance of interleukin-6 synthesized by stromal cells in response to cancer cells.Leukemia inhibitory factor secretion is a predictor and indicator of early progenitor status in adult bone marrow stromal cells.Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigms.Pharmaceutical modulation of canonical Wnt signaling in multipotent stromal cells for improved osteoinductive therapy.Osteoblastogenesis and tumor growth in myeloma.Advances in the understanding of myeloma bone disease and tumour growth.Novel therapeutic targets in myeloma bone disease.Fibroblast activation protein protects bortezomib-induced apoptosis in multiple myeloma cells through β-catenin signaling pathwayMultiple myeloma mesenchymal stromal cells: Contribution to myeloma bone disease and therapeuticsBone disease in multiple myeloma: pathophysiology and management.Dickkopf-1 is a key regulator of myeloma bone disease: opportunities and challenges for therapeutic interventionInterleukin-6 in bone metastasis and cancer progression.Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory propertiesDifferential expression of DKK-1 binding receptors on stromal cells and myeloma cells results in their distinct response to secreted DKK-1 in myeloma.CYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone diseaseThe effects of promoter methylation on downregulation of DAZAP2 in multiple myeloma cell lines.Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells.p21CIP-1/WAF-1 induction is required to inhibit prostate cancer growth elicited by deficient expression of the Wnt inhibitor Dickkopf-1.Evidence of a role for activation of Wnt/beta-catenin signaling in the resistance of plasma cells to lenalidomide.Human bone marrow-derived mesenchymal stem cells.Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networksGLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment.Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages.Mesenchymal stromal cells promote tumor growth through the enhancement of neovascularization.Pre-activation of mesenchymal stem cells with TNF-α, IL-1β and nitric oxide enhances its paracrine effects on radiation-induced intestinal injuryBone disease in multiple myeloma and precursor disease: novel diagnostic approaches and implications on clinical management.Targeting bone as a therapy for myeloma.The immune microenvironment of myelomaEx Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche.Myeloma cells inhibit osteogenic differentiation of mesenchymal stem cells and kill osteoblasts via TRAIL-induced apoptosis.The Wnt inhibitor dickkopf-1: a link between breast cancer and bone metastases.Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft modelMesenchymal stem cell-based therapy: a new paradigm in regenerative medicineMacrophages and mesenchymal stromal cells support survival and proliferation of multiple myeloma cells.Evolving paradigms for repair of tissues by adult stem/progenitor cells (MSCs).Role of the microenvironment in multiple myeloma bone disease.
P2860
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P2860
A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
A crosstalk between myeloma ce ...... ogression in multiple myeloma.
@en
type
label
A crosstalk between myeloma ce ...... ogression in multiple myeloma.
@en
prefLabel
A crosstalk between myeloma ce ...... ogression in multiple myeloma.
@en
P2860
P50
P1433
P1476
A crosstalk between myeloma ce ...... rogression in multiple myeloma
@en
P2093
Lisa Deininger
Scott D Olson
P2860
P304
P356
10.1634/STEMCELLS.2005-0220
P577
2005-11-17T00:00:00Z