Loss of the hSNF5 gene concomitantly inactivates p21CIP/WAF1 and p16INK4a activity associated with replicative senescence in A204 rhabdoid tumor cells.
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The epigenomics of cancerEpigenetics in cancerTherapeutically targeting cyclin D1 in primary tumors arising from loss of Ini1.Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitorsRB1CC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer.Reexpression of hSNF5 in malignant rhabdoid tumor cell lines causes cell cycle arrest through a p21(CIP1/WAF1)-dependent mechanismPotent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen.Rhabdoid tumor: gene expression clues to pathogenesis and potential therapeutic targets.BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancerThe SWI/SNF subunit/tumor suppressor BAF47/INI1 is essential in cell cycle arrest upon skeletal muscle terminal differentiation.Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth.SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development.HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.SNF5 reexpression in malignant rhabdoid tumors regulates transcription of target genes by recruitment of SWI/SNF complexes and RNAPII to the transcription start site of their promoters.p16INK4A and p14ARF tumor suppressor pathways are deregulated in malignant rhabdoid tumors.SWItching on the transcriptional circuitry in melanoma.BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrestIdentification of a core member of the SWI/SNF complex, BAF155/SMARCC1, as a human tumor suppressor gene.SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.MYC interaction with the tumor suppressive SWI/SNF complex member INI1 regulates transcription and cellular transformation.The role of INI1/hSNF5 in gene regulation and cancer.The role of SMARCB1/INI1 in development of rhabdoid tumor.Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteinsChromatin: a molecular interface between cancer and aging.Epigenetic aberrations during oncogenesis.Rhabdoid tumors: an initial clue to the role of chromatin remodeling in cancer.Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway.Molecular diagnostics in soft tissue sarcomas and gastrointestinal stromal tumors.Construction of a computable network model for DNA damage, autophagy, cell death, and senescence.Singular v dual inhibition of SNF2L and its isoform, SNF2LT, have similar effects on DNA damage but opposite effects on the DNA damage response, cancer cell growth arrest and apoptosis.Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability.Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes.Atypical teratoid/ rhabdoid tumor, an immunohistochemical study of potential diagnostic and prognostic markers.Molecular mechanisms of cellular senescence and immortalization of human cells.SMARCB1/INI1 inactivation in renal medullary carcinoma.Cancer epigenetics: Moving forward.
P2860
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P2860
Loss of the hSNF5 gene concomitantly inactivates p21CIP/WAF1 and p16INK4a activity associated with replicative senescence in A204 rhabdoid tumor cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Loss of the hSNF5 gene concomi ...... in A204 rhabdoid tumor cells.
@en
type
label
Loss of the hSNF5 gene concomi ...... in A204 rhabdoid tumor cells.
@en
prefLabel
Loss of the hSNF5 gene concomi ...... in A204 rhabdoid tumor cells.
@en
P2093
P1433
P1476
Loss of the hSNF5 gene concomi ...... in A204 rhabdoid tumor cells.
@en
P2093
Aubri L Charboneau
Bernard E Weissman
Bryan L Betz
Jingjing Chai
P304
10192-10198
P356
10.1158/0008-5472.CAN-05-1896
P407
P577
2005-11-01T00:00:00Z