Smad7 induces G0/G1 cell cycle arrest in mesenchymal cells by inhibiting the expression of G1 cyclins.

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Nuclear Smad7 Overexpressed in Mesenchymal Cells Acts as a Transcriptional Corepressor by Interacting with HDAC-1 and E2F to Regulate Cell Cycle.Human amniotic epithelial cells inhibit growth of epithelial ovarian cancer cells via TGF‑β1-mediated cell cycle arrest.

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Smad7 induces G0/G1 cell cycle arrest in mesenchymal cells by inhibiting the expression of G1 cyclins.

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http://www.wikidata.org/entity/Q40351576

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2005 nî lūn-bûn

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2005年の論文

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2005年論文

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Smad7 induces G0/G1 cell cycle ...... the expression of G1 cyclins.

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type

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Smad7 induces G0/G1 cell cycle ...... the expression of G1 cyclins.

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Smad7 induces G0/G1 cell cycle ...... the expression of G1 cyclins.

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Smad7 induces G0/G1 cell cycle ...... the expression of G1 cyclins.

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Kenji Okazaki

http://www.w3.org/2001/XMLSchema#string

Koki Kitamura

http://www.w3.org/2001/XMLSchema#string

Ruriko Sakamoto

http://www.w3.org/2001/XMLSchema#string

Shin-ichi Aota

http://www.w3.org/2001/XMLSchema#string

Takashi Emori

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TGF-beta signal transduction

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.

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537-552

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scholarly article

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10.1111/J.1440-169X.2005.00829.X

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2005-10-01T00:00:00Z

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16287485

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Smad7 induces G0/G1 cell cycle arrest in mesenchymal cells by inhibiting the expression of G1 cyclins.

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P2860

P2860

Smad7 induces G0/G1 cell cycle arrest in mesenchymal cells by inhibiting the expression of G1 cyclins.

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