Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays.
about
Therapeutic potential of the inhibition of the retinoic acid hydroxylases CYP26A1 and CYP26B1 by xenobiotics.Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase.CYP24A1 inhibition facilitates the anti-tumor effect of vitamin D3 on colorectal cancer cells.Synthesis of benzyl substituted naphthalenes from benzylidene tetralones.The role of CYP26 enzymes in retinoic acid clearance.Improved Homology Model of the Human all-trans Retinoic Acid Metabolizing Enzyme CYP26A1.Crystal structure of (E)-2-[(2-bromopyridin-3-yl)methyl-idene]-6-meth-oxy-3,4-di-hydro-naphthalen-1(2H)-one and 3-[(E)-(6-meth-oxy-1-oxo-1,2,3,4-tetra-hydro-naphthalen-2-ylidene)meth-yl]pyridin-2(1H)-one.Design and synthesis of substituted imidazole and triazoleN-phenylbenzo[d]oxazolamine inhibitors of retinoic acid metabolizing enzyme CYP26
P2860
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P2860
Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Novel tetralone-derived retino ...... and MCF-7 CYP26A1 cell assays.
@en
type
label
Novel tetralone-derived retino ...... and MCF-7 CYP26A1 cell assays.
@en
prefLabel
Novel tetralone-derived retino ...... and MCF-7 CYP26A1 cell assays.
@en
P2093
P50
P356
P1476
Novel tetralone-derived retino ...... and MCF-7 CYP26A1 cell assays
@en
P2093
Bronwen A J Evans
Carole Elford
Laetitia Jarno
Li-Ling Ooi
Michael P Coogan
Mohamed Sayed Gomaa
Richard McClelland
Robert Ian Nicholson
P304
P356
10.1021/JM0501681
P407
P577
2005-11-01T00:00:00Z