Identification of Epstein-Barr Virus Replication Proteins in Burkitt's Lymphoma Cells.Induction of p16(INK4a) is the major barrier to proliferation when Epstein-Barr virus (EBV) transforms primary B cells into lymphoblastoid cell lines.Evaluation of a prediction protocol to identify potential targets of epigenetic reprogramming by the cancer associated Epstein Barr virusEpigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor.bZIP proteins of human gammaherpesviruses.Epstein-Barr virus transcription factor Zta acts through distal regulatory elements to directly control cellular gene expression.DNA-damage response pathways triggered by viral replication.Loss of functional pRB is not a ubiquitous feature of B-cell malignanciesGenome-wide analyses of Zta binding to the Epstein-Barr virus genome reveals interactions in both early and late lytic cycles and an epigenetic switch leading to an altered binding profile.Strain variation in Epstein-Barr virus immediate early genes.Bioimpedance analysis for the characterization of breast cancer cells in suspension.Functional interaction between Epstein-Barr virus replication protein Zta and host DNA damage response protein 53BP1.Mutation of a single amino acid residue in the basic region of the Epstein-Barr virus (EBV) lytic cycle switch protein Zta (BZLF1) prevents reactivation of EBV from latency.KIPase activity is a novel caspase-like activity associated with cell proliferation.Dynamic chromatin environment of key lytic cycle regulatory regions of the Epstein-Barr virus genome.Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27(KIP1) in transformed lymphoid cells.Cell cycle arrest following exposure of EBV-immortalised B-cells to gamma irradiation correlates with inhibition of cdk2 activity.The efficient and rapid import of a peptide into primary B and T lymphocytes and a lymphoblastoid cell line.Reduced signal transduction through glucocorticoid receptor in Burkitt's lymphoma cell lines.Investigation of the multimerization region of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) protein K-bZIP: the proposed leucine zipper region encodes a multimerization domain with an unusual structure.Unexpected structure of Epstein-Barr virus lytic cycle activator Zta.Epigenetic control of Epstein-Barr virus transcription - relevance to viral life cycle?p16(INK4A)-independence of Epstein-Barr virus-induced cell proliferation and virus latency.Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta.Cell cycle-dependent caspase-like activity that cleaves p27KIP1 is the β1 subunit of the 20S proteasomeIdentifying the Cellular Interactome of Epstein-Barr Virus Lytic Regulator Zta Reveals Cellular Targets Contributing to Viral Replication
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description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Alison J Sinclair
@es
Alison J. Sinclair
@en
Alison J. Sinclair
@nl
type
label
Alison J Sinclair
@es
Alison J. Sinclair
@en
Alison J. Sinclair
@nl
prefLabel
Alison J Sinclair
@es
Alison J. Sinclair
@en
Alison J. Sinclair
@nl
P106
P1153
7202756304
P21
P31
P496
0000-0001-8510-8691
P569
2000-01-01T00:00:00Z