A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.
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Small Rab GTPase Rab7b promotes megakaryocytic differentiation by enhancing IL-6 production and STAT3-GATA-1 associationProtein-arginine methyltransferase 1 suppresses megakaryocytic differentiation via modulation of the p38 MAPK pathway in K562 cellsCalcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cellsAcadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell deathSynergistic effect of hydrogen peroxide on polyploidization during the megakaryocytic differentiation of K562 leukemia cells by PMA.Platelet protein kinase C-theta deficiency with human RUNX1 mutation: PRKCQ is a transcriptional target of RUNX1.Hyaluronan Depolymerization by Megakaryocyte Hyaluronidase-2 Is Required for Thrombopoiesis.Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagyLoss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genesBCR-ABL but not JAK2 V617F inhibits erythropoiesis through the Ras signal by inducing p21CIP1/WAF1.Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells.Protein kinase C signalling in leukemia.Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell deathExtracellular DNA traps released by acute promyelocytic leukemia cells through autophagyNovel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.Inhibitory effects of megakaryocytic cells in prostate cancer skeletal metastasis.Pathogenic old world hantaviruses infect renal glomerular and tubular cells and induce disassembling of cell-to-cell contacts.Ganglioside GM3 is required for caffeic acid phenethyl ester-induced megakaryocytic differentiation of human chronic myelogenous leukemia K562 cells.Megakaryocytic differentiation in human chronic myelogenous leukemia K562 cells induced by ionizing radiation in combination with phorbol 12-myristate 13-acetateTAT-CC fusion protein depresses the oncogenicity of BCR-ABL in vitro and in vivo through interrupting its oligomerization.Potentiated activation of VLA-4 and VLA-5 accelerates proplatelet-like formation.p22phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation.Role of metallothionein in differentiation of leukemia cells.A proinflammatory cytokine interleukin-32beta promotes the production of an anti-inflammatory cytokine interleukin-10.Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells.Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition.Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms.Effects of radiation on the maturation of megakaryocytes.Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation.Vibsanol A induces differentiation of acute myeloid leukemia cells via activation of the PKC signaling pathway and induction of ROS.ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.Reactive oxygen species in haematopoiesis: leukaemic cells take a walk on the wild side.
P2860
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P2860
A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A survey of the signaling path ...... ular and c-DNA array analysis.
@en
type
label
A survey of the signaling path ...... ular and c-DNA array analysis.
@en
prefLabel
A survey of the signaling path ...... ular and c-DNA array analysis.
@en
P2093
P50
P356
P1433
P1476
A survey of the signaling path ...... cular and c-DNA array analysis
@en
P2093
J-P Cassuto
N Belhacene
P Colosetti
P2888
P304
P356
10.1038/SJ.ONC.1209119
P407
P577
2006-02-01T00:00:00Z
P5875
P6179
1029031185