The nuclear-envelope protein and transcriptional repressor LAP2beta interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation.
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The nuclear envelopathies and human diseasesEmerin-prelamin A interplay in human fibroblastsThe inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphologyNuclear neighborhoods and gene expressionAnchoring a Leviathan: How the Nuclear Membrane Tethers the GenomeEpigenetic modulators, modifiers and mediators in cancer aetiology and progressionHistones and histone modifications in perinuclear chromatin anchoring: from yeast to manThe nuclear envelope as a chromatin organizerHerpesviruses and intermediate filaments: close encounters with the third typeLamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biologyPhysiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear EdgeHDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeuticsNuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinasesO-Linked β-N-acetylglucosamine (O-GlcNAc) regulates emerin binding to barrier to autointegration factor (BAF) in a chromatin- and lamin B-enriched "niche".An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.Recruitment to the nuclear periphery can alter expression of genes in human cells.MAPK signaling pathways and HDAC3 activity are disrupted during differentiation of emerin-null myogenic progenitor cells.Dynamic chromatin organization during foregut development mediated by the organ selector gene PHA-4/FoxAGenome-wide analysis links emerin to neuromuscular junction activity in Caenorhabditis elegans.Lamin-binding ProteinsLAP2 is widely overexpressed in diverse digestive tract cancers and regulates motility of cancer cells.NET23/STING promotes chromatin compaction from the nuclear envelopeAdvancing our understanding of functional genome organisation through studies in the fission yeast.Role of histone deacetylases in gene regulation at nuclear lamina.Lmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes.Role of the nuclear envelope in genome organization and gene expression.On emerging nuclear order.Histone acetyltransferase hALP and nuclear membrane protein hsSUN1 function in de-condensation of mitotic chromosomes.Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins.The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture.Embryonic and adult isoforms of XLAP2 form microdomains associated with chromatin and the nuclear envelope.Emerin in health and disease.Olfactory receptor genes expressed in distinct lineages are sequestered in different nuclear compartments.Nuclear lamins: key regulators of nuclear structure and activitiesButyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genesGlobal reorganization of budding yeast chromosome conformation in different physiological conditionsNetworking in the nucleus: a spotlight on LEM-domain proteinsNuclear membrane diversity: underlying tissue-specific pathologies in disease?The nuclear envelope protein emerin binds directly to histone deacetylase 3 (HDAC3) and activates HDAC3 activity.Nuclear mechanics in cancer
P2860
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P2860
The nuclear-envelope protein and transcriptional repressor LAP2beta interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The nuclear-envelope protein a ...... uces histone H4 deacetylation.
@en
type
label
The nuclear-envelope protein a ...... uces histone H4 deacetylation.
@en
prefLabel
The nuclear-envelope protein a ...... uces histone H4 deacetylation.
@en
P2093
P356
P1476
The nuclear-envelope protein a ...... uces histone H4 deacetylation.
@en
P2093
Amos J Simon
Einav Nili Gal-Yam
Gideon Rechavi
Ninette Amariglio
Orit Geller
Raz Somech
Sigal Shaklai
P304
P356
10.1242/JCS.02521
P407
P577
2005-09-01T00:00:00Z