Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells
about
Gene mutations and response to treatment with all-trans retinoic acid in elderly patients with acute myeloid leukemia. Results from the AMLSG Trial AML HD98B.Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide.Molecular pathways: regulation and therapeutic implications of multidrug resistanceTAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells.Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy.Repositioning of Tyrosine Kinase Inhibitors as Antagonists of ATP-Binding Cassette Transporters in Anticancer Drug ResistanceA PU.1 suppressive target gene, metallothionein 1G, inhibits retinoic acid-induced NB4 cell differentiationScreening of deoxyribozyme with high reversal efficiency against multidrug resistance in breast carcinoma cells.The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cellsHistone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells.Drug resistance: still a daunting challenge to the successful treatment of AML.The antiepileptic and anticancer agent, valproic acid, induces P-glycoprotein in human tumour cell lines and in rat liverThailandepsins are new small molecule class I HDAC inhibitors with potent cytotoxic activity in ovarian cancer cells: a preclinical study of epigenetic ovarian cancer therapyPrediction of Nepsilon-acetylation on internal lysines implemented in Bayesian Discriminant MethodElevated expression of MDR1 associated with Line-1 hypomethylation in esophageal squamous cell carcinomaP-glycoprotein Mediates Postoperative Peritoneal Adhesion Formation by Enhancing Phosphorylation of the Chloride Channel-3.Romidepsin (FK228) combined with cisplatin stimulates DNA damage-induced cell death in ovarian cancer.Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?Induction of chemoresistance by all-trans retinoic acid via a noncanonical signaling in multiple myeloma cells.miR-137 regulates the constitutive androstane receptor and modulates doxorubicin sensitivity in parental and doxorubicin-resistant neuroblastoma cellsEpigenetic regulation of drug processing genes.NF-Y and the transcriptional activation of CCAAT promoters.Epigenetics in acute promyelocytic leukaemia pathogenesis and treatment response: a TRAnsition to targeted therapies.HDAC inhibitor-induced drug resistance involving ATP-binding cassette transporters (Review)Exosomal miRNA Analysis in Non-small Cell Lung Cancer (NSCLC) Patients' Plasma Through qPCR: A Feasible Liquid Biopsy Tool.The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model.The DAC system and associations with acute leukemias and myelodysplastic syndromes.Valproic acid inhibits adhesion of vincristine- and cisplatin-resistant neuroblastoma tumour cells to endothelium.Modulation of P-glycoprotein function by sphingosine kinase-1 in brain endothelial cells.Doxorubicin-conjugated dexamethasone induced MCF-7 apoptosis without entering the nucleus and able to overcome MDR-1-induced resistanceOverview of the Classical Histone Deacetylase Enzymes and Histone Deacetylase Inhibitors
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P2860
Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Up-regulation of MDR1 and indu ...... e promyelocytic leukemia cells
@en
type
label
Up-regulation of MDR1 and indu ...... e promyelocytic leukemia cells
@en
prefLabel
Up-regulation of MDR1 and indu ...... e promyelocytic leukemia cells
@en
P2093
P2860
P1433
P1476
Up-regulation of MDR1 and indu ...... e promyelocytic leukemia cells
@en
P2093
Isao Nagaoka
Linhua Jin
Mark Munsell
Rooha Contractor
Wendy D Schober
Yuko Tsutsumi-Ishii
P2860
P304
P356
10.1182/BLOOD-2004-10-4126
P407
P577
2005-10-13T00:00:00Z