High susceptibility of human dendritic cells to invasion by the intracellular pathogens Brucella suis, B. abortus, and B. melitensis.
about
Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection.Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1.Comparative proteomics analyses reveal the virB of B. melitensis affects expression of intracellular survival related proteins.Human brucellosis is characterized by an intense Th1 profile associated with a defective monocyte function.In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice.Brucella melitensis invades murine erythrocytes during infection.Caspase-2-dependent dendritic cell death, maturation, and priming of T cells in response to Brucella abortus infection.Full restoration of Brucella-infected dendritic cell functionality through Vγ9Vδ2 T helper type 1 crosstalk.The Attenuated Brucella abortus Strain 19 Invades, Persists in, and Activates Human Dendritic Cells, and Induces the Secretion of IL-12p70 but Not IL-23Establishment of systemic Brucella melitensis infection through the digestive tract requires urease, the type IV secretion system, and lipopolysaccharide O antigenComplete genome-wide screening and subtractive genomic approach revealed new virulence factors, potential drug targets against bio-war pathogen Brucella melitensis 16M.Invasive Escherichia coli vaccines expressing Brucella melitensis outer membrane proteins 31 or 16 or periplasmic protein BP26 confer protection in mice challenged with B. melitensis.B Lymphocytes provide an infection niche for intracellular bacterium Brucella abortus.HIV-1 antisense transcription is preferentially activated in primary monocyte-derived cells.Brucella discriminates between mouse dendritic cell subsets upon in vitro infection.Treatment of neurobrucellosis: what is known and what remains to be answered.Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella.Natural antibody contributes to host defense against an attenuated Brucella abortus virB mutant.Survival of the fittest: how Brucella strains adapt to their intracellular niche in the host.Nondividing but metabolically active gamma-irradiated Brucella melitensis is protective against virulent B. melitensis challenge in mice.A T4SS Effector Targets Host Cell Alpha-Enolase Contributing to Brucella abortus Intracellular Lifestyle.Brucellosis and type IV secretion.Internal affairs: investigating the Brucella intracellular lifestyle.Host-Brucella interactions and the Brucella genome as tools for subunit antigen discovery and immunization against brucellosis.Serving the new masters - dendritic cells as hosts for stealth intracellular bacteria.Brucella melitensis cyclic di-GMP phosphodiesterase BpdA controls expression of flagellar genesA novel trafficking signal within the HLA-C cytoplasmic tail allows regulated expression upon differentiation of macrophages.Discordance in the effects of Yersinia pestis on the dendritic cell functions manifested by induction of maturation and paralysis of migration.Brucella suis prevents human dendritic cell maturation and antigen presentation through regulation of tumor necrosis factor alpha secretion"If you bring an alarm, we will destroy it," said Brucella to the host cell.Interaction of Brucella suis and Brucella abortus rough strains with human dendritic cells.Chronic brucellosis patients retain low frequency of CD4+ T-lymphocytes expressing CD25 and CD28 after Escherichia coli LPS stimulation of PHA-cultured PBMCs.Brucella requires a functional Type IV secretion system to elicit innate immune responses in mice.Variability in the response of canine and human dendritic cells stimulated with Brucella canis.Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review.
P2860
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P2860
High susceptibility of human dendritic cells to invasion by the intracellular pathogens Brucella suis, B. abortus, and B. melitensis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
High susceptibility of human d ...... B. abortus, and B. melitensis.
@en
type
label
High susceptibility of human d ...... B. abortus, and B. melitensis.
@en
prefLabel
High susceptibility of human d ...... B. abortus, and B. melitensis.
@en
P2093
P2860
P1476
High susceptibility of human d ...... B. abortus, and B. melitensis
@en
P2093
Chantal Cazevieille
Elisabeth Billard
Jacques Dornand
P2860
P304
P356
10.1128/IAI.73.12.8418-8424.2005
P407
P577
2005-12-01T00:00:00Z