Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan.
about
A novel molecular diagnostic of glioblastomas: detection of an extracellular fragment of protein tyrosine phosphatase muCancer cell death enhances the penetration and efficacy of oncolytic herpes simplex virus in tumorsProteolytic cleavage of protein tyrosine phosphatase mu regulates glioblastoma cell migrationThe status of gene therapy for brain tumorsCancer immunotherapy via combining oncolytic virotherapy with chemotherapy: recent advancesOncolytic herpes simplex virus-based strategies: toward a breakthrough in glioblastoma therapyCyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging.Combination treatment with oncolytic Vaccinia virus and cyclophosphamide results in synergistic antitumor effects in human lung adenocarcinoma bearing miceOncolytic herpes simplex virus vectors and chemotherapy: are combinatorial strategies more effective for cancer?Construction and properties of a herpes simplex virus 1 designed to enter cells solely via the IL-13alpha2 receptorModulation of the pentose phosphate pathway alters phase I metabolism of testosterone and dextromethorphan in HepG2 cells.Design and application of oncolytic HSV vectors for glioblastoma therapy.Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma.ONCOLYTIC HERPES SIMPLEX VIRUS 1 (HSV-1) VECTORS: INCREASING TREATMENT EFFICACY AND RANGE THROUGH STRATEGIC VIRUS DESIGN.Oncolytic herpes simplex virus expressing yeast cytosine deaminase: relationship between viral replication, transgene expression, prodrug bioactivation.Oncolytic measles virus encoding thyroidal sodium iodide symporter for squamous cell cancer of the head and neck radiovirotherapy.Oncolytic measles virus prolongs survival in a murine model of cerebral spinal fluid-disseminated medulloblastomaOptimization of adenoviral vector-mediated transgene expression in the canine brain in vivo, and in canine glioma cells in vitro.Designing Herpes Viruses as Oncolytics.Gene therapeutics: the future of brain tumor therapy?Dynamic Quantitative T1 Mapping in Orthotopic Brain Tumor Xenografts.Combinatorial strategies for oncolytic herpes simplex virus therapy of brain tumors.Oncolytic herpes viruses, chemotherapeutics, and other cancer drugsEnhancement of intratumoral cyclophosphamide pharmacokinetics and antitumor activity in a P450 2B11-based cancer gene therapy model.Molecular strategies for the treatment of malignant glioma--genes, viruses, and vaccines.Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with ProdrugsGene therapy: the end of the rainbow?An optical probe for noninvasive molecular imaging of orthotopic brain tumors overexpressing epidermal growth factor receptor.The potential application of a transcriptionally regulated oncolytic herpes simplex virus for human cancer therapy.Pharmacologic and chemical adjuvants in tumor virotherapy.REO-10: a phase I study of intravenous reovirus and docetaxel in patients with advanced cancer.Regional liver therapy using oncolytic virus to target hepatic colorectal metastases.HSV Recombinant Vectors for Gene Therapy.Genetic therapy for the nervous system.Rethinking herpes simplex virus: the way to oncolytic agents.Bugs and drugs: oncolytic virotherapy in combination with chemotherapy.Pharmacological modulation of anti-tumor immunity induced by oncolytic viruses.Novel cryo-imaging of the glioma tumor microenvironment reveals migration and dispersal pathways in vivid three-dimensional detail.Oncolytic viruses-immunotherapeutics on the rise.Arming viruses in multi-mechanistic oncolytic viral therapy: current research and future developments, with emphasis on poxviruses.
P2860
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P2860
Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Brain tumor oncolysis with rep ...... clophosphamide and irinotecan.
@en
type
label
Brain tumor oncolysis with rep ...... clophosphamide and irinotecan.
@en
prefLabel
Brain tumor oncolysis with rep ...... clophosphamide and irinotecan.
@en
P2093
P1433
P1476
Brain tumor oncolysis with rep ...... clophosphamide and irinotecan.
@en
P2093
Dianne M Finkelstein
E Antonio Chiocca
Edyta Tyminski
Janice L Hyatt
Kinya Terada
Mary K Danks
Philip M Potter
Stanley Leroy
Yoshinaga Saeki
P304
P356
10.1158/0008-5472.CAN-05-0154
P407
P577
2005-08-01T00:00:00Z