Mast cell tryptase controls paracellular permeability of the intestine. Role of protease-activated receptor 2 and beta-arrestins.
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Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2Protease-activated receptor 2 has pivotal roles in cellular mechanisms involved in experimental periodontitisMast Cells and Irritable Bowel Syndrome: From the Bench to the BedsideMultifaceted role of β-arrestins in inflammation and diseaseRegulation of type 2 immunity to helminths by mast cellsGut/brain axis and the microbiotaBrain-gut microbiome interactions and functional bowel disordersThe multifaceted mast cell in inflammatory bowel diseaseRedefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of MrgprsChronic peripheral administration of corticotropin-releasing factor causes colonic barrier dysfunction similar to psychological stressApplication of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteinsRole of Corticotropin-releasing Factor in Gastrointestinal Permeability.Gene and protein expression of protease-activated receptor 2 in structural and inflammatory cells in the nasal mucosa in seasonal allergic rhinitis.Phosphorylation of protease-activated receptor-2 differentially regulates desensitization and internalization.Antibiotics Suppress Activation of Intestinal Mucosal Mast Cells and Reduce Dietary Lipid Absorption in Sprague-Dawley RatsEarly weaning stress impairs development of mucosal barrier function in the porcine intestine.In vitro model for IgE mediated food allergy.Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cellsThe Relationship between Small-Intestinal Bacterial Overgrowth and Intestinal Permeability in Patients with Irritable Bowel Syndrome.Mast cell deficiency exacerbates inflammatory bowel symptoms in interleukin-10-deficient miceEarly life stress triggers persistent colonic barrier dysfunction and exacerbates colitis in adult IL-10-/- mice.Activation of protease activated receptor 2 by exogenous agonist exacerbates early radiation injury in rat intestineCRF induces intestinal epithelial barrier injury via the release of mast cell proteases and TNF-α.TNFAIP3 facilitates degradation of microbial antigen SEB in enterocytesMast cell proteases as pharmacological targetsThe role of mast cells in functional GI disorders.Apical and basolateral pools of proteinase-activated receptor-2 direct distinct signaling events in the intestinal epithelium.Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2Mechanisms of disease: protease functions in intestinal mucosal pathobiologyHeat stress reduces intestinal barrier integrity and favors intestinal glucose transport in growing pigs.Principles and clinical implications of the brain-gut-enteric microbiota axis.Intestinal epithelial barrier dysfunction in food hypersensitivity.Mast cell activation is involved in stress-induced epithelial barrier dysfunction in the esophagus.Pea (Pisum sativum L.) seed albumin extracts show anti-inflammatory effect in the DSS model of mouse colitis.Diarrhoea-predominant IBS patients show mast cell activation and hyperplasia in the jejunum.Corticotropin releasing factor signaling in colon and ileum: regulation by stress and pathophysiological implicationsThe joint power of sex and stress to modulate brain-gut-microbiota axis and intestinal barrier homeostasis: implications for irritable bowel syndrome.Molecular and cellular mechanisms of tight junction dysfunction in the irritable bowel syndromeProtein Kinase D and Gβγ Subunits Mediate Agonist-evoked Translocation of Protease-activated Receptor-2 from the Golgi Apparatus to the Plasma Membrane.VEGF is involved in the increase of dermal microvascular permeability induced by tryptase.
P2860
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P2860
Mast cell tryptase controls paracellular permeability of the intestine. Role of protease-activated receptor 2 and beta-arrestins.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Mast cell tryptase controls pa ...... receptor 2 and beta-arrestins.
@en
type
label
Mast cell tryptase controls pa ...... receptor 2 and beta-arrestins.
@en
prefLabel
Mast cell tryptase controls pa ...... receptor 2 and beta-arrestins.
@en
P2093
P2860
P356
P1476
Mast cell tryptase controls pa ...... receptor 2 and beta-arrestins.
@en
P2093
Anne-Marie Coelho
Dalila Darmoul
Eileen F Grady
Graeme S Cottrell
Mary Perdue
Nigel W Bunnett
Pamela Singh
Ping-Chang Yang
Silvia Amadesi
Toshiyuki Saito
P2860
P304
31936-31948
P356
10.1074/JBC.M506338200
P407
P50
P577
2005-07-18T00:00:00Z