Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance.
about
The role of megadose CD34+ progenitor cells in the treatment of leukemia patients without a matched donor and in tolerance induction for organ transplantation.Genetically haploidentical stem cell transplantation for acute leukemia.Bone marrow-derived dendritic cell progenitors (NLDC 145+, MHC class II+, B7-1dim, B7-2-) induce alloantigen-specific hyporesponsiveness in murine T lymphocytesTriptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F.The combination of chemotherapy and systemic immunotherapy and the concept of cure in murine leukemia and lymphoma.Uncoupling of T cell receptor zeta chain function during the induction of anergy by the superantigen, staphylococcal enterotoxin ACostimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipientsAntigen-presenting cell engineering. The molecular toolboxIL-12 is an effective adjuvant to recombinant vaccinia virus-based tumor vaccines: enhancement by simultaneous B7-1 expression.Interleukin 2 restores CD3-zeta chain expression but fails to generate tumour-specific lytic activity in tumour-infiltrating lymphocytes derived from human colorectal hepatic metastases.Protection against lethal toxic shock by targeted disruption of the CD28 geneB7-2 expressed on EL4 lymphoma suppresses antitumor immunity by an interleukin 4-dependent mechanism.Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy.Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells.Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses.CD28 aptamers as powerful immune response modulatorsMolecular and cellular mechanisms of photocarcinogenesis.Chronic cardiac rejection in the LEW to F344 rat model. Blockade of CD28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis."No donor"? Consider a haploidentical transplantNon-glycosylated human B7-1(CD80) retains the capacity to bind its counter-receptors.Developing therapeutic 'arrows' with the precision of William Tell: the time has come for targeted therapies in kidney disease.CD28 is required for optimal induction, but not maintenance, of vaccine-induced immunity to Blastomyces dermatitidis.B7 costimulation plays an important role in protection from herpes simplex virus type 2-mediated pathology.Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: candidates for a novel form of specific immunotherapyAdvances in haploidentical stem cell transplantation.Expression of B7 costimulatory molecules by salivary gland epithelial cells in patients with Sjögren's syndrome.Neonatal oral tolerance.ICAM-1 costimulation induces IL-2 but inhibits IL-10 production in superantigen-activated human CD4+ T cells.Enhancement of class II-restricted T cell responses by costimulatory NK receptors for class I MHC proteins.The role of B7-1/B7-2:CD28/CLTA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response.CD80, CD86 and CD40 provide accessory signals in a multiple-step T-cell activation model.Cytotoxic T-lymphocyte (CTL) responses against acute or chronic myeloid leukemia.The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells.Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled byDifferential expression of protein tyrosine kinases and their phosphorylation in murine Th1 cells anergized with class II MHC-peptide complexes.A blood-borne antigen induces rapid T-B cell contact: a potential mechanism for tolerance induction.Enhancement of T cell activation by immobilized hu5C8 (anti-CD40L) monoclonal antibodyAccumulation of CTLA-4 expressing T lymphocytes in the germinal centres of human lymphoid tissuesStrategies for preventing porcine xenograft rejection: recent progress and future developments
P2860
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P2860
Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance.
@en
type
label
Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance.
@en
prefLabel
Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance.
@en
P2093
P1476
Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance.
@en
P2093
G J Freeman
J G Gribben
L M Nadler
V A Boussiotis
P304
P356
10.1016/0952-7915(94)90087-6
P577
1994-10-01T00:00:00Z