Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus.
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The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcriptionRegulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1The 19 s proteasome subcomplex establishes a specific protein interaction network at the promoter for stimulated transcriptional initiation in vivo.The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancerRegulation of estrogen receptor α N-terminus conformation and function by peptidyl prolyl isomerase Pin1A mechanistic study of the effect of doxorubicin/adriamycin on the estrogen response in a breast cancer modelEstrogens, selective estrogen receptor modulators, and a selective estrogen receptor down-regulator inhibit endothelial production of tissue factor pathway inhibitor 1.Palmitoylation regulates 17β-estradiol-induced estrogen receptor-α degradation and transcriptional activityProteasome inhibition represses ERalpha gene expression in ER+ cells: a new link between proteasome activity and estrogen signaling in breast cancerAn innovative method to classify SERMs based on the dynamics of estrogen receptor transcriptional activity in living animals.Proteolytic turnover of the Gal4 transcription factor is not required for function in vivo.Fulvestrant-induced cell death and proteasomal degradation of estrogen receptor α protein in MCF-7 cells require the CSK c-Src tyrosine kinase.Automethylation of CARM1 allows coupling of transcription and mRNA splicingPhosphorylation of Estrogen Receptor α at serine 118 directs recruitment of promoter complexes and gene-specific transcriptionIsoform-specific regulation of a steroid hormone nuclear receptor by an E3 ubiquitin ligase in Drosophila melanogasterA kinetic model identifies phosphorylated estrogen receptor-α (ERα) as a critical regulator of ERα dynamics in breast cancerPeptidylprolyl Isomerase Pin1 Directly Enhances the DNA Binding Functions of Estrogen Receptor α.Ubiquitylation of nuclear receptors: new linkages and therapeutic implications.Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors.Post-translational modifications of nuclear receptors and human diseasep38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription.Previous Midlife Oestradiol Treatment Results in Long-Term Maintenance of Hippocampal Oestrogen Receptor α Levels in Ovariectomised Rats: Mechanisms and Implications for Memory.Molecular mechanisms of the physiological functions of the aryl hydrocarbon (dioxin) receptor, a multifunctional regulator that senses and responds to environmental stimuliStable inhibition of specific estrogen receptor α (ERα) phosphorylation confers increased growth, migration/invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells.Transcription in four dimensions: nuclear receptor-directed initiation of gene expressionNuclear ubiquitin proteasome degradation affects WRKY45 function in the rice defense program.Phosphorylation of activation function-1 regulates proteasome-dependent nuclear mobility and E6-associated protein ubiquitin ligase recruitment to the estrogen receptor beta1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE) disrupts the estrogen-androgen balance regulating the growth of hormone-dependent breast cancer cells.CARM1 automethylation is controlled at the level of alternative splicing.Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer.Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation.Blockade of estrogen action upregulates estrogen receptor-alpha mRNA in the fetal brain.Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer.Sodium arsenite inhibited genomic estrogen signaling but induced pERα (Ser118) via MAPK pathway in breast cancer cells.Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells.Turning off estrogen receptor beta-mediated transcription requires estrogen-dependent receptor proteolysis.CK1delta modulates the transcriptional activity of ERalpha via AIB1 in an estrogen-dependent manner and regulates ERalpha-AIB1 interactions.Chromatin context dominates estrogen regulation of pS2 gene expression.Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor-Positive Breast Cancer.A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses
P2860
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P2860
Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Differential regulation of est ...... gen receptor alpha N terminus.
@en
type
label
Differential regulation of est ...... gen receptor alpha N terminus.
@en
prefLabel
Differential regulation of est ...... gen receptor alpha N terminus.
@en
P2093
P2860
P1476
Differential regulation of est ...... gen receptor alpha N terminus.
@en
P2093
Amy M Fowler
Christopher C Valley
Elaine T Alarid
Lindsay Hill
Mara T Mashek
Natalia M Solodin
P2860
P304
P356
10.1128/MCB.25.13.5417-5428.2005
P407
P577
2005-07-01T00:00:00Z