Glioblastomas induce T-lymphocyte death by two distinct pathways involving gangliosides and CD70.
about
Immune Evasion Strategies of GlioblastomaImmunosuppressive strategies that are mediated by tumor cellsHighly enhanced expression of CD70 on human T-lymphotropic virus type 1-carrying T-cell lines and adult T-cell leukemia cells.The ganglioside GM3 is associated with cisplatin-induced apoptosis in human colon cancer cellsElevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction.TGF-β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin's lymphoma.Overview of cellular immunotherapy for patients with glioblastoma.Subtyping glioblastoma by combining miRNA and mRNA expression data using compressed sensing-based approachMechanisms of malignant glioma immune resistance and sources of immunosuppressionT cells redirected against CD70 for the immunotherapy of CD70-positive malignanciesGBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway.Melanoma Expressed-CD70 Is Regulated by RhoA and MAPK Pathways without Affecting Vemurafenib Treatment Activity.Immunotherapy targets in pediatric cancer.Characterization of the human T cell response to in vitro CD27 costimulation with varlilumabImmunosuppressive mechanisms in glioblastoma.Memory T cells in human tumor and chronic inflammatory microenvironments: sleeping beauties re-awakened by a cytokine kiss.CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death.T-cell death and cancer immune tolerance.CD70 as a therapeutic target in human malignancies.Gliomas promote immunosuppression through induction of B7-H1 expression in tumor-associated macrophagesImmunotherapeutic approaches for gliomaGD3, an overexpressed tumor-derived ganglioside, mediates the apoptosis of activated but not resting T cells.Expression of CD70 (CD27L) Is Associated With Epithelioid and Sarcomatous Features in IDH-Wild-Type Glioblastoma.Therapeutic targeting of CD70 and CD27.Clinical significance of CD70 expression on T cells in human T-lymphotropic virus type-1 carriers and adult T cell leukemia/ lymphoma patients.Chimeric antigen receptors for treatment of glioblastoma: a practical review of challenges and ways to overcome them.Site-specific anti-tumor immunity: differences in DC function, TGF-beta production and numbers of intratumoral Foxp3+ Treg.Immune escape for renal cell carcinoma: CD70 mediates apoptosis in lymphocytes.Endogenous GD3 ganglioside induces apoptosis in U-1242 MG glioma cells.CD70, a novel target of CAR T-cell therapy for gliomas.The costimulatory molecule CD70 is regulated by distinct molecular mechanisms and is associated with overall survival in diffuse large B-cell lymphoma.Mechanisms of Immune Evasion and Immune Modulation by Lymphoma Cells.
P2860
Q26765855-6402AE66-86EF-4FB9-8C35-E1CE6C4D275DQ29636247-7241ED4E-B2E7-4340-860A-D9AC20ECB86BQ33318640-DBA4AD3A-2613-4E8D-83F2-24829E5DCDFFQ33609838-6CB5C3AA-2708-49D5-B00B-AAD5B304C922Q33932479-E29A6DAD-47E8-4A1E-A491-B8F3BEC208A7Q34090686-06E25C13-4D51-4479-A44B-A2427903D39AQ34189694-7899FA96-3D14-4F8B-A9E3-D5F7CBF438F9Q34545716-571FD65D-A424-4DE8-9BF8-0B2D999583AAQ34661793-C4F1AF18-ACA5-4C03-BBE1-498D399CA3DCQ34923799-C0B66512-E4F6-4853-8014-90A0B87CCCD7Q35726496-1F97806E-134B-4354-ABBE-ECF5DCEFFDE0Q35909427-3D4B0098-E6EF-4276-B50E-130E30F3F4F3Q35971029-9D6B4D5B-8498-4758-8C78-A88CEC5807A7Q36203023-744D1312-7E37-4437-9210-4A5DF63BBFD6Q36224048-6EFE9FE1-16FF-4912-A461-0F89B5A68A23Q36569011-E41082B7-0149-49E2-85B1-A258AB1B68CBQ36998531-ACEE37DD-54B0-44D6-A363-4FBD07C5F098Q37002795-F0B9C933-07AD-4849-AC06-035255515AE4Q37082785-DAF69A92-9A9E-41C5-AD0A-AD244A3681C8Q37092938-44C3FA96-5544-4C7F-82F8-7EA206ACEFCAQ37267793-35F38D59-0AF7-437D-9BDE-9ECCA35492D1Q38496048-DC977E39-A603-4431-8128-8D40C84707A2Q38633640-2D6DC3F0-5DC2-469A-AF24-144D5031E8C4Q38749841-C3C51515-C979-4039-A1A8-1FAC57310452Q38863823-B755BE67-A8B3-4CEE-88AD-85E88DFED4C2Q38987239-26AB2060-C2E8-4EF2-B111-E7E3C60324E9Q39865711-5A4FEC9C-72DB-4588-800F-80183F4AD140Q40203455-630A69B0-695A-404F-8FC4-7616374A4FD5Q40324177-A5A00ECA-DD64-40DD-A9EC-028BCC315CF6Q48223703-79289DCE-B21B-4533-A7C6-3E0A1A713DD5Q50953796-83CEE39E-AA30-4BDB-A2AE-230962B20709Q52643503-045619C4-8EE5-4574-A011-075848CC7AC3
P2860
Glioblastomas induce T-lymphocyte death by two distinct pathways involving gangliosides and CD70.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Glioblastomas induce T-lymphoc ...... volving gangliosides and CD70.
@en
type
label
Glioblastomas induce T-lymphoc ...... volving gangliosides and CD70.
@en
prefLabel
Glioblastomas induce T-lymphoc ...... volving gangliosides and CD70.
@en
P2093
P1433
P1476
Glioblastomas induce T-lymphoc ...... nvolving gangliosides and CD70
@en
P2093
Ali Chahlavi
Amy L Richmond
Charles Tannenbaum
Gene Barnett
James H Finke
Michael Vogelbaum
Patricia Rayman
Renliang Zhang
P304
P356
10.1158/0008-5472.CAN-04-4395
P407
P577
2005-06-01T00:00:00Z