DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells.
about
Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repairThe mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayTwo novel human and mouse DNA polymerases of the polX familyAssociation of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair.poliota, a remarkably error-prone human DNA polymeraseDNA polymerase family X: function, structure, and cellular rolesManaging DNA polymerases: coordinating DNA replication, DNA repair, and DNA recombinationCharacterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe.Increased learning and brain long-term potentiation in aged mice lacking DNA polymerase μMolecular Dynamics Simulations and Structural Analysis to Decipher Functional Impact of a Twenty Residue Insert in the Ternary Complex of Mus musculus TdT IsoformCrystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferaseStructural insight into the substrate specificity of DNA Polymerase muSolution Structure of Polymerase μ's BRCT Domain Reveals an Element Essential for Its Role in Nonhomologous End Joining †Sustained active site rigidity during synthesis by human DNA polymerase μImplication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts.XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gapsEnd-bridging is required for pol mu to efficiently promote repair of noncomplementary ends by nonhomologous end joiningA physical and functional interaction between yeast Pol4 and Dnl4-Lif1 links DNA synthesis and ligation in nonhomologous end joining.Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzymeIdentification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repairTerminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histoneIdentification of functional domains in TdIF1 and its inhibitory mechanism for TdT activitySibling rivalry: competition between Pol X family members in V(D)J recombination and general double strand break repairDNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein APolymerase mu is up-regulated during the T cell-dependent immune response and its deficiency alters developmental dynamics of spleen centroblastsDNA repair in Drosophila: insights from the Drosophila genome sequence.A novel DNA polymerase homologous to Escherichia coli DNA polymerase I from a higher plant, rice (Oryza sativa L.).Numt-mediated double-strand break repair mitigates deletions during primate genome evolutionDNA polymerase β contains a functional nuclear localization signal at its N-terminus.Nonhomologous end joining: a good solution for bad endsHypermutation in bacteria and other cellular systemsA new class of errant DNA polymerases provides candidates for somatic hypermutation.Transcription, beta-like DNA polymerases and hypermutationDNA polymerase mu, a candidate hypermutase?Nuclear DNA polymerase beta from Leishmania infantum. Cloning, molecular analysis and developmental regulation.Human DNA polymerase iota promiscuous mismatch extension.Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities.Eukaryotic DNA polymerases: proposal for a revised nomenclature.Error-prone DNA repair activity during somatic hypermutation in shark B lymphocytes
P2860
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P2860
DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
DNA polymerase mu (Pol mu), ho ...... A mutator in eukaryotic cells.
@en
type
label
DNA polymerase mu (Pol mu), ho ...... A mutator in eukaryotic cells.
@en
prefLabel
DNA polymerase mu (Pol mu), ho ...... A mutator in eukaryotic cells.
@en
P2093
P2860
P356
P1433
P1476
DNA polymerase mu (Pol mu), ho ...... A mutator in eukaryotic cells.
@en
P2093
C Martínez-A
M A González
M García-Díaz
O Domínguez
T Kirchhoff
T Laín de Lera
P2860
P304
P356
10.1093/EMBOJ/19.7.1731
P407
P577
2000-04-01T00:00:00Z