Optimal tRNA((Ser)Sec) gene activity requires an upstream SPH motif.
about
Two distinct domains in Staf to selectively activate small nuclear RNA-type and mRNA promotersStaf, a promiscuous activator for enhanced transcription by RNA polymerases II and IIIZNF76 and ZNF143 are two human homologs of the transcriptional activator StafStaf, a novel zinc finger protein that activates the RNA polymerase III promoter of the selenocysteine tRNA geneThe molecular biology of selenocysteineTranscriptional regulation of the mouse cytosolic chaperonin subunit gene Ccta/t-complex polypeptide 1 by selenocysteine tRNA gene transcription activating factor family zinc finger proteinsRNA polymerase III-mediated transcription of the trypanosome U2 small nuclear RNA gene is controlled by both intragenic and extragenic regulatory elementsMolecular cloning and characterization of the murine staf cDNA encoding a transcription activating factor for the selenocysteine tRNA gene in mouse mammary gland.Comparison of chicken 7SK and U6 RNA polymerase III promoters for short hairpin RNA expressionThe scaRNA2 is produced by an independent transcription unit and its processing is directed by the encoding regionThe distal sequence element of the selenocysteine tRNA gene is a tissue-dependent enhancer essential for mouse embryogenesistRNASec is transcribed by RNA polymerase II in Trypanosoma brucei but not in humansSmall nuclear RNA genes: a model system to study fundamental mechanisms of transcription.A genome scale location analysis of human Staf/ZNF143-binding sites suggests a widespread role for human Staf/ZNF143 in mammalian promoters.Structural requirements for the functional activity of a U1 snRNA gene enhancer.Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp).Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development.The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice.Transcription factor abundance controlled by an auto-regulatory mechanism involving a transcription start site switch.Functional characterization of elements in a human U6 small nuclear RNA gene distal control region.An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene.Structural organization of Staf-DNA complexes.Point mutations 5' to the tRNA selenocysteine TATA box alter RNA polymerase III transcription by affecting the binding of TBP.Ex vivo correction of selenoprotein N deficiency in rigid spine muscular dystrophy caused by a mutation in the selenocysteine codon.Identification and characterisation of the porcine 7SK RNA polymerase III promoter for short hairpin RNA expression.Maximization of selenocysteine tRNA and U6 small nuclear RNA transcriptional activation achieved by flexible utilization of a Staf zinc finger.
P2860
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P2860
Optimal tRNA((Ser)Sec) gene activity requires an upstream SPH motif.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Optimal tRNA((Ser)Sec) gene activity requires an upstream SPH motif.
@en
type
label
Optimal tRNA((Ser)Sec) gene activity requires an upstream SPH motif.
@en
prefLabel
Optimal tRNA((Ser)Sec) gene activity requires an upstream SPH motif.
@en
P2093
P2860
P356
P1476
Optimal tRNA((Ser)Sec) gene activity requires an upstream SPH motif.
@en
P2093
P2860
P304
P356
10.1093/NAR/20.2.203
P577
1992-01-01T00:00:00Z