Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia. - Wikidata - wikimedia - TriplyDB

Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia.

Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia.

http://www.wikidata.org/entity/Q40413223

about

A novel role of Sprouty 2 in regulating cellular apoptosis White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies Enteric nervous system development: migration, differentiation, and disease Hyperplasia of interstitial cells of cajal in sprouty homolog 4 deficient mice Disorders of gastrointestinal hypomotility A functional interaction between sprouty proteins and caveolin-1 CrkL is a novel target of Sprouty2 in fibroblast growth factor signaling.Regulation of sprouty stability by Mnk1-dependent phosphorylation.The VASP-Spred-Sprouty domain puzzle.Genetic model system studies of the development of the enteric nervous system, gut motility and Hirschsprung's disease Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development.G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes Sprouty2 downregulates angiogenesis during mouse skin wound healing.Sprouty1 and Sprouty2 limit both the size of the otic placode and hindbrain Wnt8a by antagonizing FGF signaling Megaesophagus in a line of transgenic rats: a model of achalasia.Mice that express farnesylated versions of prelamin A in neurons develop achalasia.Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interaction Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility Development of enteric neuron diversity.Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor 3 signaling.Sprouty1 is a candidate tumor-suppressor gene in medullary thyroid carcinoma Molecular signaling along the anterior-posterior axis of early palate development.Molecular clocks underlying vertebrate embryo segmentation: A 10-year-old hairy-go-round.The tyrosine phosphatase Shp2 (PTPN11) in cancer.Suppression of Sproutys has a therapeutic effect for a mouse model of ischemia by enhancing angiogenesis.NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner Fibroblast growth factors and epidermal growth factor cooperate with oocyte-derived members of the TGFbeta superfamily to regulate Spry2 mRNA levels in mouse cumulus cells.Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction.Achalasia: will genetic studies provide insights?Development and developmental disorders of the enteric nervous system.Hirschsprung disease: a developmental disorder of the enteric nervous system.Receptor tyrosine kinase (RTK) signalling in the control of neural stem and progenitor cell (NSPC) development.MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility.Enteric nervous system development: A crest cell's journey from neural tube to colon.Gene-environment interactions and the enteric nervous system: Neural plasticity and Hirschsprung disease prevention Regulation of SPRY3 by X chromosome and PAR2-linked promoters in an autism susceptibility region.Mouse models of Hirschsprung disease and other developmental disorders of the enteric nervous system: Old and new players.Comparative Microarray Analysis of Proliferating and Differentiating Murine ENS Progenitor Cells.Sprouty4 interferes with cell proliferation and migration of breast cancer-derived cell lines.

P2860

Q24302565-F3EC0416-9CB7-4E7D-9454-E86218B4723F Q26750556-CD312777-9E2D-4A39-83C5-8D81BDA9D7A7 Q26849660-D4AE939F-1FAB-47CB-A9DE-99AC92B6B865 Q27308910-5684B1CA-C8CF-4452-B72C-A0B029B203A7 Q28070278-B8DEFA23-5B14-4A34-9222-8867702A54E1 Q28254941-1F5CE827-F64C-438E-BF7F-28E081391CA1 Q30156967-5BE3B4A9-0075-441B-8219-29AFA87E9533 Q30446670-7ED153B7-4DED-426D-B8D1-65FFEE02C31C Q33343173-36F1C4E8-06D5-405F-BFD5-4A359D5F8B31 Q33699347-97BE8E99-FF97-44AE-9843-7F67B1FC7F6E Q33714250-29F3600B-D764-4B3F-AA06-C3DC8E472BEF Q34181221-B3419F69-C237-4EAE-8F26-AC1E707AF62E Q34598338-1A21C72D-371A-442E-A27D-AF3903405EF6 Q34600328-24901F5B-5795-4AC7-981A-9683FE22FA3D Q34785950-CCE3B3AC-A075-42B6-8DF1-1509A3B5C4E7 Q35219230-6E9F8D2C-6168-4E8D-A8F0-4AED28324E7B Q35524497-CFF81249-DEC6-4902-A2F2-41FAD9D4CEEB Q35739181-B79895ED-9C1A-42B4-B44F-84F2B07B8393 Q35739636-C6923A9D-C690-4623-BF56-633B6743CC3D Q35832069-72C5D9DF-6B56-497A-A79A-8FFB16E70000 Q35857107-9E909C6C-9290-4D34-967B-A5410D4F43BE Q36043347-AB32B1EF-25CF-480D-AF19-FDAC1BCEB337 Q36516812-B53BE2AC-6009-47B2-B84D-47E56DAF67E2 Q36864807-1CA4F00E-D739-4456-A6E7-9BD80811F3ED Q37088972-317947DB-ED95-46DF-B014-A7F03F385B91 Q37173668-A0411CBD-3274-410D-A6F1-D288866FBC73 Q37327781-C9024291-C6F6-4162-8EC7-75392E1B16B5 Q37404719-8E28186E-D72D-4C6F-8659-26B2EA8EBC23 Q37452346-93445A9A-5FBF-45E3-9B0E-DB64E41E820E Q37779272-A34629A0-6FC8-4CCA-8BE0-5F139669B4B0 Q38066359-0CEB58F2-2DD4-491C-A5A4-E8FDBD6E6A2C Q38116935-259A72B3-8033-464D-9B2F-E3F2F845694B Q38132066-66FDE6ED-747B-4D03-995A-497EC93DC437 Q38261355-1FDAB2B2-224A-4DBD-A28F-2EAE7DCD701A Q38558481-2460820C-7677-49F1-85FE-9470096A63B2 Q38782466-72FD51A3-D96D-4B85-991D-512C0876A5D9 Q38862335-C778FB4F-0222-4F9F-9131-21BAA85FA0BB Q38883845-34B628CE-E8D8-4DCC-A767-C9BD61014B60 Q38928721-F72E6C83-0A13-4C6C-A39F-6A6790D6E477 Q39036313-F525B0F6-AA57-45E2-9772-CAD84B591650

P2860

Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia.

http://www.wikidata.org/entity/Q40413223

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

2005年论文

@zh

2005年论文

@zh-cn

name

Loss of mammalian Sprouty2 lea ...... asia and esophageal achalasia.

@en

type

label

Loss of mammalian Sprouty2 lea ...... asia and esophageal achalasia.

@en

prefLabel

Loss of mammalian Sprouty2 lea ...... asia and esophageal achalasia.

@en

P1433

Q40413223-9B4CACC2-9EB5-4560-9C4A-9289E778504B

P1476

Q40413223-09CD738C-2754-41EE-9A31-C8EDB95D2D50

P2093

Q40413223-0905F88E-328F-4F5B-895F-78224895B608

Q40413223-1859F962-0D7E-4B88-B502-B30E53C2AB52

Q40413223-21CE21D9-61FF-40B8-9A33-B1A4212893F3

Q40413223-2E9377D5-3638-4B1C-85DE-404ACE515DED

Q40413223-5DAE9C05-1640-48EC-8FB2-445DF43E875C

Q40413223-5E8DDDC4-A41B-41A5-90C3-69F9148E6091

Q40413223-A7A915D3-86BB-49D6-A11A-B7DDD1491005

Q40413223-B67DAE56-151A-4850-8899-702701392832

Q40413223-BAE9A552-4ECD-4742-A429-E3EA4F51183F

Q40413223-CB694B2C-24DF-4DDD-A88A-18CD3D1BE1A2

P2860

Q40413223-57933CEB-97DA-4DD0-BA9B-945E35683869

Q40413223-58C92AA1-A5F6-488A-B0B7-C75B414931C6

Q40413223-59BEB068-95A1-4077-980F-E95580392774

Q40413223-89C5A45E-F10C-446E-8B52-6A5221DE3451

Q40413223-8D203AF6-1F36-4019-B90B-BE61B0172A60

Q40413223-9ED0765E-645A-43A5-9F7F-3E44A131DF13

Q40413223-CBDF996B-2875-4EAB-8B45-38268DB456AD

Q40413223-DEEF9499-C188-442E-AAE0-4360AD738718

Q40413223-E6E5E5E1-62D3-4C91-850A-78E348013A18

P2888

Q40413223-59E65DF7-5EDA-45A0-BD58-578CD516939D

P304

Q40413223-B335F868-7E3F-4959-A817-74DBEADC6DD4

P31

Q40413223-B145A780-21DD-4398-B03B-DB9F147D60E0

P356

Q40413223-A043437A-B244-48DC-A588-00FC08478A10

P407

Q40413223-745B84E2-8CE3-4E21-9D45-DC618D2D1375

P433

Q40413223-504CC1DD-6654-413C-900B-CD86141F20BA

P478

Q40413223-976CD122-F0A6-410D-A070-635E46DBBAC5

P577

Q40413223-4879048C-32BD-41DF-9D73-4BAF4A6FA69C

P6179

Q40413223-314E462F-454C-4D55-8C15-B5C76AF27D00

P698

Q40413223-C0051E3C-2F68-4BD9-832F-F2F77EF08B62

P356

P1433

Nature Neuroscience

P1476

Loss of mammalian Sprouty2 lea ...... asia and esophageal achalasia.

@en

P2093

Akihiko Yoshimura

http://www.w3.org/2001/XMLSchema#string

Atsuo Sasaki

http://www.w3.org/2001/XMLSchema#string

Atsushi Nonami

http://www.w3.org/2001/XMLSchema#string

Daigo Yoshiga

http://www.w3.org/2001/XMLSchema#string

Hitoshi Ishibashi

http://www.w3.org/2001/XMLSchema#string

Junji Nishimura

http://www.w3.org/2001/XMLSchema#string

Kei-ichiro Nakamura

http://www.w3.org/2001/XMLSchema#string

Koji Taniguchi

http://www.w3.org/2001/XMLSchema#string

Maiko Moriyama

http://www.w3.org/2001/XMLSchema#string

Mika Sasaki

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF

The mechanism for the contraction induced by leukotriene C4 in guinea-pig taenia coli

Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction

Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling

Spred is a Sprouty-related suppressor of Ras signalling.

Modulation of signalling by Sprouty: a developing story.

Enteric nervous system progenitors are coordinately controlled by the G protein-coupled receptor EDNRB and the receptor tyrosine kinase RET.

A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma

P2888

P304

855-857

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NN1485

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

8

http://www.w3.org/2001/XMLSchema#string

P577

2005-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1005002794

http://www.w3.org/2001/XMLSchema#string

P698

15937482

http://www.w3.org/2001/XMLSchema#string