(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.
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Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acidInternational Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligandsEssential roles of four-carbon backbone chemicals in the control of metabolismRole of β-hydroxybutyrate, its polymer poly-β-hydroxybutyrate and inorganic polyphosphate in mammalian health and diseaseCollateral damage: microbiota-derived metabolites and immune function in the antibiotic eraRegulation of Ketone Body Metabolism and the Role of PPARαGut microbiota-derived short-chain Fatty acids, T cells, and inflammationGPR109A and vascular inflammationNicotinic acid receptor agonists differentially activate downstream effectorsNiacin stimulates adiponectin secretion through the GPR109A receptorThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsThe hypophagic response to heat stress is not mediated by GPR109A or peripheral β-OH butyratePathway of programmed cell death and oxidative stress induced by β-hydroxybutyrate in dairy cow abomasum smooth muscle cells and in mouse gastric smooth muscle.Oral β-hydroxybutyrate increases ketonemia, decreases visceral adipocyte volume and improves serum lipid profile in Wistar rats.Acute metabolic responses to a high-carbohydrate meal in outpatients with type 2 diabetes treated with a low-carbohydrate diet: a crossover meal tolerance study.Screening of Different Organs of Rats for HCA2 Receptor mRNAAre Short Chain Fatty Acids in Gut Microbiota Defensive Players for Inflammation and Atherosclerosis?Future of GPR109A agonists in the treatment of dyslipidaemia.Ketone bodies as signaling metabolites.Role of pyruvate dehydrogenase kinase 4 in regulation of blood glucose levels.Upregulation of GPR109A in Parkinson's diseaseNiacin activates the PI3K/Akt cascade via PKC- and EGFR-transactivation-dependent pathways through hydroxyl-carboxylic acid receptor 2.Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells.Ketone bodies as a therapeutic for Alzheimer's disease.Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson's disease models are mediated by GPR109A-dependent mechanisms.Distinct pathways of ERK1/2 activation by hydroxy-carboxylic acid receptor-1β-Hydroxybutyric sodium salt inhibition of growth hormone and prolactin secretion via the cAMP/PKA/CREB and AMPK signaling pathways in dairy cow anterior pituitary cells.The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory diseaseβ-hydroxybutyrate: much more than a metaboliteIFNγ Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer.The effect of short-chain fatty acids on human monocyte-derived dendritic cellsFumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS.Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.Proteomic Identification of Target Proteins of Thiodigalactoside in White Adipose Tissue from Diet-Induced Obese Rats.Nonequilibrium thermodynamics and energy efficiency in weight loss diets.Biological roles and therapeutic potential of hydroxy-carboxylic Acid receptors.Protection by beta-Hydroxybutyric acid against insulin glycation, lipid peroxidation and microglial cell apoptosis.Ketone Bodies and Exercise Performance: The Next Magic Bullet or Merely Hype?GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.
P2860
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P2860
(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
(D)-beta-Hydroxybutyrate inhib ...... icotinic acid receptor PUMA-G.
@en
type
label
(D)-beta-Hydroxybutyrate inhib ...... icotinic acid receptor PUMA-G.
@en
prefLabel
(D)-beta-Hydroxybutyrate inhib ...... icotinic acid receptor PUMA-G.
@en
P2093
P2860
P356
P1476
(D)-beta-Hydroxybutyrate inhib ...... icotinic acid receptor PUMA-G.
@en
P2093
Andrew K P Taggart
Daniel Connolly
Jeremy Richman
Kang Cheng
Kenneth Wu
M Gerard Waters
Marc Ippolito
P2860
P304
26649-26652
P356
10.1074/JBC.C500213200
P407
P577
2005-06-01T00:00:00Z