(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G. - Wikidata - wikimedia - TriplyDB

(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.

(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.

http://www.wikidata.org/entity/Q40414685

about

Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands Essential roles of four-carbon backbone chemicals in the control of metabolism Role of β-hydroxybutyrate, its polymer poly-β-hydroxybutyrate and inorganic polyphosphate in mammalian health and disease Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era Regulation of Ketone Body Metabolism and the Role of PPARα Gut microbiota-derived short-chain Fatty acids, T cells, and inflammation GPR109A and vascular inflammation Nicotinic acid receptor agonists differentially activate downstream effectors Niacin stimulates adiponectin secretion through the GPR109A receptor The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors The hypophagic response to heat stress is not mediated by GPR109A or peripheral β-OH butyrate Pathway of programmed cell death and oxidative stress induced by β-hydroxybutyrate in dairy cow abomasum smooth muscle cells and in mouse gastric smooth muscle.Oral β-hydroxybutyrate increases ketonemia, decreases visceral adipocyte volume and improves serum lipid profile in Wistar rats.Acute metabolic responses to a high-carbohydrate meal in outpatients with type 2 diabetes treated with a low-carbohydrate diet: a crossover meal tolerance study.Screening of Different Organs of Rats for HCA2 Receptor mRNA Are Short Chain Fatty Acids in Gut Microbiota Defensive Players for Inflammation and Atherosclerosis?Future of GPR109A agonists in the treatment of dyslipidaemia.Ketone bodies as signaling metabolites.Role of pyruvate dehydrogenase kinase 4 in regulation of blood glucose levels.Upregulation of GPR109A in Parkinson's disease Niacin activates the PI3K/Akt cascade via PKC- and EGFR-transactivation-dependent pathways through hydroxyl-carboxylic acid receptor 2.Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells.Ketone bodies as a therapeutic for Alzheimer's disease.Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson's disease models are mediated by GPR109A-dependent mechanisms.Distinct pathways of ERK1/2 activation by hydroxy-carboxylic acid receptor-1 β-Hydroxybutyric sodium salt inhibition of growth hormone and prolactin secretion via the cAMP/PKA/CREB and AMPK signaling pathways in dairy cow anterior pituitary cells.The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease β-hydroxybutyrate: much more than a metabolite IFNγ Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer.The effect of short-chain fatty acids on human monocyte-derived dendritic cells Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS.Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.Proteomic Identification of Target Proteins of Thiodigalactoside in White Adipose Tissue from Diet-Induced Obese Rats.Nonequilibrium thermodynamics and energy efficiency in weight loss diets.Biological roles and therapeutic potential of hydroxy-carboxylic Acid receptors.Protection by beta-Hydroxybutyric acid against insulin glycation, lipid peroxidation and microglial cell apoptosis.Ketone Bodies and Exercise Performance: The Next Magic Bullet or Merely Hype?GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.

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P2860

(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.

http://www.wikidata.org/entity/Q40414685

description

2005 nî lūn-bûn

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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2005年论文

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2005年论文

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name

(D)-beta-Hydroxybutyrate inhib ...... icotinic acid receptor PUMA-G.

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(D)-beta-Hydroxybutyrate inhib ...... icotinic acid receptor PUMA-G.

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(D)-beta-Hydroxybutyrate inhib ...... icotinic acid receptor PUMA-G.

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Journal of Biological Chemistry

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(D)-beta-Hydroxybutyrate inhib ...... icotinic acid receptor PUMA-G.

@en

P2093

Andrew K P Taggart

http://www.w3.org/2001/XMLSchema#string

Chen Liaw

http://www.w3.org/2001/XMLSchema#string

Daniel Connolly

http://www.w3.org/2001/XMLSchema#string

Jeremy Richman

http://www.w3.org/2001/XMLSchema#string

Kang Cheng

http://www.w3.org/2001/XMLSchema#string

Kenneth Wu

http://www.w3.org/2001/XMLSchema#string

Lan Jin

http://www.w3.org/2001/XMLSchema#string

M Gerard Waters

http://www.w3.org/2001/XMLSchema#string

Marc Ippolito

http://www.w3.org/2001/XMLSchema#string

Ning Ren

http://www.w3.org/2001/XMLSchema#string

P2860

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

Molecular identification of nicotinic acid receptor

Discovery and mapping of ten novel G protein-coupled receptor genes

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

Molecular identification of high and low affinity receptors for nicotinic acid

PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

Starvation in man

The benefits of niacin in atherosclerosis.

Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes.

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26649-26652

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scholarly article

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10.1074/JBC.C500213200

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29

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280

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P50

Stefan Offermanns

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2005-06-01T00:00:00Z

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P698

15929991

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