Na+ site in blood coagulation factor IXa: effect on catalysis and factor VIIIa binding.
about
Mechanism of the Ca2+-induced Enhancement of the Intrinsic Factor VIIa ActivityNa+ binding to meizothrombin desF1Mutant N143P Reveals How Na+ Activates ThrombinMolecular basis of factor IXa recognition by heparin-activated antithrombin revealed by a 1.7-A structure of the ternary complexRigidification of the autolysis loop enhances Na+ binding to thrombinFunctional role of residue 193 (chymotrypsin numbering) in serine proteases: influence of side chain length and beta-branching on the catalytic activity of blood coagulation factor XIa.Evidence of the E*-E equilibrium from rapid kinetics of Na+ binding to activated protein C and factor Xa.Redesigning allosteric activation in an enzyme.Role of Na+ and K+ in enzyme function.Thrombin.Exosites in the substrate specificity of blood coagulation reactions.Activation mechanisms of coagulation factor IX.Structural biology of factor VIIa/tissue factor initiated coagulationThe conformational switch from the factor X zymogen to protease state mediates exosite expression and prothrombinase assembly.The factor VIIIa C2 domain (residues 2228-2240) interacts with the factor IXa Gla domain in the factor Xase complex.High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa.Characterization of a monoclonal antibody B1 that recognizes phosphorylated Ser-158 in the activation peptide region of human coagulation factor IX.Role of glycine 221 in catalytic activity of hyaluronan-binding protein 2.Murine thrombin lacks Na+ activation but retains high catalytic activity.Rapidly stopping hemorrhage by enhancing blood clotting at an opened wound using chitosan/polylactic acid/polycaprolactone wound dressing device.
P2860
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P2860
Na+ site in blood coagulation factor IXa: effect on catalysis and factor VIIIa binding.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Na+ site in blood coagulation factor IXa: effect on catalysis and factor VIIIa binding.
@en
type
label
Na+ site in blood coagulation factor IXa: effect on catalysis and factor VIIIa binding.
@en
prefLabel
Na+ site in blood coagulation factor IXa: effect on catalysis and factor VIIIa binding.
@en
P2093
P1476
Na+ site in blood coagulation factor IXa: effect on catalysis and factor VIIIa binding.
@en
P2093
Akash Mathur
Amy E Schmidt
Jonathan E Stewart
S Paul Bajaj
Sriram Krishnaswamy
P356
10.1016/J.JMB.2005.04.052
P407
P577
2005-07-01T00:00:00Z