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Oxidative Stress Signaling in Alzheimers DiseaseRegulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegenerationNeuronal response in Alzheimer's and Parkinson's disease: the effect of toxic proteins on intracellular pathwaysNeuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylationInflammatory process in Alzheimer's DiseaseDesigned protein tetramer zipped together with a hydrophobic Alzheimer homology: A structural clue to amyloid assemblySolution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domainOxidative stress in Alzheimer's and Parkinson's diseases: insights from the yeast Saccharomyces cerevisiaeThe alpha-to-beta conformational transition of Alzheimer's Abeta-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis suggests the location of beta conformation seedingβ-Amyloid1-42, HIV-1Ba-L (clade B) infection and drugs of abuse induced degeneration in human neuronal cells and protective effects of ashwagandha (Withania somnifera) and its constituent Withanolide ANeuropeptide Y protects rat cortical neurons against β-amyloid toxicity and re-establishes synthesis and release of nerve growth factorMultiple caspases are involved in beta-amyloid-induced neuronal apoptosisI. Study of protein aggregation due to heat denaturation: A structural approach using circular dichroism spectroscopy, nuclear magnetic resonance, and static light scattering.NMR studies in aqueous solution fail to identify significant conformational differences between the monomeric forms of two Alzheimer peptides with widely different plaque-competence, A beta(1-40)(ox) and A beta(1-42)(ox).Natural product extracts that reduce accumulation of the Alzheimer's amyloid beta peptide: selective reduction in A beta42.Estradiol prevents olfactory dysfunction induced by A-β 25-35 injection in hippocampus.The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons.Interleukin-3 prevents neuronal death induced by amyloid peptideAmyloid-beta peptide binds to microtubule-associated protein 1B (MAP1B).Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neuronsActivity and architecture of pyroglutamate-modified amyloid-β (AβpE3-42) poresDisordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs.Molecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseasesThe plasma membrane redox system is impaired by amyloid β-peptide and in the hippocampus and cerebral cortex of 3xTgAD mice.Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disordersArgpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy.Stabilities and conformations of Alzheimer's beta -amyloid peptide oligomers (Abeta 16-22, Abeta 16-35, and Abeta 10-35): Sequence effects.Feasibility of β-sheet breaker peptide-H102 treatment for Alzheimer's disease based on β-amyloid hypothesis.Erythropoietin prevents PC12 cells from beta-amyloid-induced apoptosis via PI3K⁄Akt pathway.The role of heat shock protein 70 in the protective effect of YC-1 on β-amyloid-induced toxicity in differentiated PC12 cells.Cerebrospinal fluid brain-derived proteins in the diagnosis of Alzheimer's disease and Creutzfeldt-Jakob disease.Ashwagandha (Withania somnifera) reverses β-amyloid1-42 induced toxicity in human neuronal cells: implications in HIV-associated neurocognitive disorders (HAND).Mass spectrometry as an efficient tool for the characterization of amyloid β peptide 25-35 self-assembly species in aggregation and inhibition studies.Chemical neuroimmunology: health in a nutshell bidirectional communication between immune and stress (limbic-hypothalamic-pituitary-adrenal) systems.Changes in the ageing brain in health and disease.Immunization against Alzheimer's beta -amyloid plaques via EFRH phage administrationInteraction of Aβ(25-35) fibrillation products with mitochondria: Effect of small-molecule natural products.Monoclonal antibodies to a 100-kd protein reveal abundant A beta-negative plaques throughout gray matter of Alzheimer's disease brains.Ginsenoside Rg1 protects against neurodegeneration by inducing neurite outgrowth in cultured hippocampal neurons.Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity.
P2860
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P2860
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
The toxicity in vitro of beta-amyloid protein.
@en
type
label
The toxicity in vitro of beta-amyloid protein.
@en
prefLabel
The toxicity in vitro of beta-amyloid protein.
@en
P2093
P2860
P356
P1433
P1476
The toxicity in vitro of beta-amyloid protein.
@en
P2093
Mortishire-Smith RJ
Pollack SJ
Shearman MS
P2860
P356
10.1042/BJ3110001
P407
P478
311 ( Pt 1)
P577
1995-10-01T00:00:00Z