Alpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress.
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New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomasVitamin E and cancer: An insight into the anticancer activities of vitamin E isomers and analogsLatest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapiesSupramolecular micellar nanoaggregates based on a novel chitosan/vitamin E succinate copolymer for paclitaxel selective delivery.MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with the mitochondrial functionMitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex IIERK2 is essential for the growth of human epithelioid malignant mesotheliomas.Effect of α-tocopheryl succinate on the molecular damage induced by indomethacin in C6 glioma cellsMitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healingSub-apoptotic dosages of pro-oxidant vitamin cocktails sensitize human melanoma cells to NK cell lysisThe Combination of α-Tocopheryl Succinate and Sodium Selenite on Breast Cancer: A Merit or a Demerit?Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II.Small mitochondria-targeting molecules as anti-cancer agents.Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death.Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.Mitochondrial targeting of α-tocopheryl succinate enhances its anti-mesothelioma efficacy.Mitochondrial Pathway of α-Tocopheryl Succinate-Induced Apoptosis in Human Epidermoid Carcinoma A431 Cells.Affinity of vitamin E analogues for the ubiquinone complex II site correlates with their toxicity to cancer cells.alpha-Tocopheryl succinate promotes selective cell death induced by vitamin K3 in combination with ascorbate.Daxx inhibits stress-induced apoptosis in cardiac myocytes.alpha-Tocopheryl succinate inhibits angiogenesis by disrupting paracrine FGF2 signalling.Mitochondria transmit apoptosis signalling in cardiomyocyte-like cells and isolated hearts exposed to experimental ischemia-reperfusion injury.Role of thioredoxin-1 in apoptosis induction by alpha-tocopheryl succinate and TNF-related apoptosis-inducing ligand in mesothelioma cells.Naringin attenuates the development of carrageenan-induced acute lung inflammation through inhibition of NF-κb, STAT3 and pro-inflammatory mediators and enhancement of IκBα and anti-inflammatory cytokines.Cross-talk of alpha tocopherol-associated protein and JNK controls the oxidative stress-induced apoptosis in prostate cancer cells.α-Tocopheryloxyacetic acid is superior to α-tocopheryl succinate in suppressing HER2-high breast carcinomas due to its higher stabilityα-Tocopheryl Succinate-Based Polymeric Nanoparticles for the Treatment of Head and Neck Squamous Cell Carcinoma
P2860
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P2860
Alpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Alpha-tocopheryl succinate inh ...... the role of oxidative stress.
@en
type
label
Alpha-tocopheryl succinate inh ...... the role of oxidative stress.
@en
prefLabel
Alpha-tocopheryl succinate inh ...... the role of oxidative stress.
@en
P2093
P356
P1476
Alpha-tocopheryl succinate inh ...... d the role of oxidative stress
@en
P2093
Antonio Procopio
Emma Swettenham
Marco Tomasetti
Michael Stapelberg
Nina Gellert
P304
25369-25376
P356
10.1074/JBC.M414498200
P407
P577
2005-05-05T00:00:00Z