The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197.
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Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197Characterization of the diphtheria tox transcript in Corynebacterium diphtheriae and Escherichia coliFactors contributing to the immunogenicity of meningococcal conjugate vaccinesA physico-chemical assessment of the thermal stability of pneumococcal conjugate vaccine componentsSubunit S1 of pertussis toxin: mapping of the regions essential for ADP-ribosyltransferase activityBiology and molecular epidemiology of diphtheria toxin and the tox gene.Expression and immunogenicity of a mutant diphtheria toxin molecule, CRM(197), and its fragments in Salmonella typhi vaccine strain CVD 908-htrA.Combined conjugate vaccines: enhanced immunogenicity with the N19 polyepitope as a carrier protein.Genome organization and pathogenicity of Corynebacterium diphtheriae C7(-) and PW8 strains.Protein carriers of conjugate vaccines: characteristics, development, and clinical trials.The respiratory syncytial virus G protein conserved domain induces a persistent and protective antibody response in rodentsSmall molecule mimetics of an HIV-1 gp41 fusion intermediate as vaccine leads.Defined conjugation of glycans to the lysines of CRM197 guided by their reactivity mapping.Vaccination of heifers with anaflatoxin improves the reduction of aflatoxin b1 carry over in milk of lactating dairy cows.Chemical synthesis of the outer core oligosaccharide of Escherichia coli R3 and immunological evaluation.Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sitesIdentification of a single amino acid substitution in the diphtheria toxin A chain of CRM 228 responsible for the loss of enzymatic activity.Patterns of binding of aluminum-containing adjuvants to Haemophilus influenzae type b and meningococcal group C conjugate vaccines and componentsHigh-level expression of a proteolytically sensitive diphtheria toxin fragment in Escherichia coliA novel glyco-conjugate vaccine against fungal pathogens.Design of highly specific cytotoxins by using trans-splicing ribozymes.Human antibody response to fragments A and B of diphtheria toxin and a synthetic peptide of amino acid residues 141-157 of fragment ATranscutaneous immunization with cross-reacting material CRM(197) of diphtheria toxin boosts functional antibody levels in mice primed parenterally with adsorbed diphtheria toxoid vaccine.Cloning, sequence determination, and expression in transfected cells of the coding sequence for the tox 176 attenuated diphtheria toxin A chain.Effect of carrier priming on immunogenicity of saccharide-protein conjugate vaccinesDiphtheria toxin and its ADP-ribosyltransferase-defective homologue CRM197 possess deoxyribonuclease activity.The history of pneumococcal conjugate vaccine development: dose selection.Role of polymer-drug conjugates in organ-specific delivery systems.Identification of diphtheria toxin R domain mutants with enhanced inhibitory activity against HB-EGF.Gene expression profile of human colon cancer cells treated with cross-reacting material 197, a diphtheria toxin non-toxic mutant.Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.Use of synthetic peptides and site-specific antibodies to localize a diphtheria toxin sequence associated with ADP-ribosyltransferase activity.Nanocarriers for brain specific delivery of anti-retro viral drugs: challenges and achievements.Water accessibility, aggregation, and motional features of polysaccharide-protein conjugate vaccines.Diphtheria toxin promoter function in Corynebacterium diphtheriae and Escherichia coliA chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assemblyRho-dependent membrane folding causes Shigella entry into epithelial cells.On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells.Identification of diphtheria toxin receptor and a nonproteinous diphtheria toxin-binding molecule in Vero cell membrane.Caspase activation as a versatile assay platform for detection of cytotoxic bacterial toxins.
P2860
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P2860
The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197.
@en
type
label
The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197.
@en
prefLabel
The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197.
@en
P2093
P2860
P356
P1476
The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197.
@en
P2093
P2860
P304
P356
10.1093/NAR/12.10.4063
P577
1984-05-01T00:00:00Z