Modification of telomeric DNA in Trypanosoma brucei; a role in antigenic variation?
about
A base called JCrystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucosebeta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres.Suppression of subtelomeric VSG switching by Trypanosoma brucei TRF requires its TTAGGG repeat-binding activity.Characterization of VSG gene expression site promoters and promoter-associated DNA rearrangement eventsTb927.10.6900 encodes the glucosyltransferase involved in synthesis of base J in Trypanosoma bruceiControl of gene expression in trypanosomes.The identification of hydroxymethyluracil in DNA of Trypanosoma bruceiHistone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma bruceiShared themes of antigenic variation and virulence in bacterial, protozoal, and fungal infections.Unusual chromatin in human telomeresMetacyclic variant surface glycoprotein genes of Trypanosoma brucei subsp. rhodesiense are activated in situ, and their expression is transcriptionally regulatedAfrican trypanosomes contain 5-methylcytosine in nuclear DNA.Molecular biology of trypanosome antigenic variationRecognition of base J in duplex DNA by J-binding protein.Biosynthesis and function of the modified DNA base beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strandsLocalization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei.A novel DNA nucleotide in Trypanosoma brucei only present in the mammalian phase of the life-cycle.Antigenic variation in Trypanosoma brucei: a telomeric expression site for variant-specific surface glycoprotein genes with novel features.The trypanosome spliced leader small RNA gene family: stage-specific modification of one of several similar dispersed genes.Structure and transcription of a telomeric surface antigen gene of Trypanosoma brucei.Trypanosome hybrids generated in tsetse flies by nuclear fusion.Telomeric localization of the modified DNA base J in the genome of the protozoan parasite Leishmania.J-binding protein increases the level and retention of the unusual base J in trypanosome DNA.A strand bias occurs in point mutations associated with variant surface glycoprotein gene conversion in Trypanosoma rhodesiense.A monocistronic transcript for a trypanosome variant surface glycoprotein.A proposed mechanism for promoter-associated DNA rearrangement events at a variant surface glycoprotein gene expression site.Site-specific interactions of JBP with base and sugar moieties in duplex J-DNA. Evidence for both major and minor groove contacts.The anatomy and transcription of a monocistronic expression site for a metacyclic variant surface glycoprotein gene in Trypanosoma brucei.
P2860
Q22066178-503C2114-64F8-4506-92C8-4056E62CDAC5Q27730858-0460463B-9128-494A-ACE6-06A59562CDDEQ30454424-2430E851-6477-4B34-86B3-78099D5389A4Q30860113-C498BCC4-D45B-409F-B7A0-B38AFB76FEE7Q33262466-A23212DA-8C9E-47C1-AABC-7B6146A30BBBQ34389666-B8FA2EB5-1578-4CCF-B26C-DBC2F4148ADEQ34720465-36385ECD-C706-4D6C-B96E-2C126F1DA0D3Q34981683-2B62A6D3-0A34-49EA-B7C3-46C62AC790C7Q35900453-B2D3B23C-41F3-40AD-9D57-0B94ECE80DC3Q36574313-6017800E-E025-4ABD-8D80-567184AD3760Q36664811-3708E260-D0FD-46A4-ACC0-A7377CB7B568Q36915257-CB755163-A6FF-4510-977C-F6A30D30917FQ36974363-8E57A160-3E89-4E97-AD3C-D3C14F1EF350Q37061546-D9B1A302-06D4-4401-884A-3E5D89EBBEB3Q38294915-73E66BF7-A03D-4313-9323-10B4268BA475Q39576095-B21D67FC-FEED-48BF-A3D1-2ED96A3C7322Q39716733-1B37A452-4E64-43D5-A4A0-0C4280FE0965Q40443898-366F9137-A9E9-463D-955C-924600E8811BQ40503295-25869C23-17F6-41BD-B0E2-7C87FDDBC253Q40532428-3ECD1825-AD80-4BBA-8057-986F2C5A8073Q40560336-6A3906BD-C7A5-469C-9658-ED267CD2D1B7Q40665866-3B4E2841-4CDC-4162-887C-6B386FF3B902Q41894668-8114AF9D-A579-4097-8E3E-2D8FB7F4B83EQ42254040-10372F69-49A3-4930-894B-9D478A3F7BD1Q42526672-C6201197-F55A-44ED-BD6F-4DD7079CD7E8Q43181774-EAD388F8-D19C-4BCD-AEC3-B7DC2CBB05B3Q43182069-127237BB-8411-4445-A393-E636CE2DFED5Q43183326-96C01E79-1744-422F-87DA-E0CE9E483929Q44005236-3F5621B7-AF28-46BD-8587-F14F50B6E084Q47958504-F87208A9-B1D7-4445-90F3-B8F3CAC53D20
P2860
Modification of telomeric DNA in Trypanosoma brucei; a role in antigenic variation?
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Modification of telomeric DNA in Trypanosoma brucei; a role in antigenic variation?
@en
type
label
Modification of telomeric DNA in Trypanosoma brucei; a role in antigenic variation?
@en
prefLabel
Modification of telomeric DNA in Trypanosoma brucei; a role in antigenic variation?
@en
P2093
P2860
P356
P1476
Modification of telomeric DNA in Trypanosoma brucei; a role in antigenic variation?
@en
P2093
Bernards A
van Harten-Loosbroek N
P2860
P304
P356
10.1093/NAR/12.10.4153
P577
1984-05-01T00:00:00Z