Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion
about
Preadministration of High-Dose Salicylates, Suppressors of NF- B Activation, May Increase the Chemosensitivity of Many Cancers: An Example of Proapoptotic Signal Modulation TherapyLoss of IkkB promotes migration and proliferation of mouse embryo fibroblast cellsRegulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticalsNew Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of AutophagyEvodiamine inhibits insulin-stimulated mTOR-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obese/diabetic miceRegulation of NF-κB activation through a novel PI-3K-independent and PKA/Akt-dependent pathway in human umbilical vein endothelial cellsEvodiamine synergizes with doxorubicin in the treatment of chemoresistant human breast cancer without inhibiting P-glycoproteinEvodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cellsAn in vitro FluoroBlok tumor invasion assay.Bone marrow mononuclear cells up-regulate toll-like receptor expression and produce inflammatory mediators in response to cigarette smoke extractInhibition of choriodecidual cytokine production and inflammatory gene expression by selective I-kappaB kinase (IKK) inhibitors.Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro.Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.Anti-Proliferative Effects of Evodiamine on Human Breast Cancer Cells.Evodia rutaecarpa and Three Major Alkaloids Abrogate Influenza A Virus (H1N1)-Induced Chemokines Production and Cell Migration.NF-kappaB and cancer: how intimate is this relationshipArvelexin from Brassica rapa suppresses NF-κB-regulated pro-inflammatory gene expression by inhibiting activation of IκB kinaseEnhanced antitumor efficacy of gemcitabine by evodiamine on pancreatic cancer via regulating PI3K/Akt pathway.Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers.Elucidating the identity of resistance mechanisms to prednisolone exposure in acute lymphoblastic leukemia cells through transcriptomic analysis: A computational approach.Expression of NF-κB and PTEN in primary epithelial ovarian carcinoma and the correlation with chemoresistance.Cancer and diet: How are they related?Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice.TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer.Simvastatin inhibits induction of matrix metalloproteinase-9 in rat alveolar macrophages exposed to cigarette smoke extractSignificance of Bcl-xL in human colon carcinoma.Targeting NF-κB and HIF-1 pathways for the treatment of cancer: part I.Anticancer drugs from traditional toxic Chinese medicines.Evodiamine induces apoptosis and enhances TRAIL-induced apoptosis in human bladder cancer cells through mTOR/S6K1-mediated downregulation of Mcl-1Evodiamine inhibits the migration and invasion of nasopharyngeal carcinoma cells in vitro via repressing MMP-2 expression.Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets.Regulation of STAT3 and NF-κB activations by S-nitrosylation in multiple myeloma.Preparation, characterization, and anticancer efficacy of evodiamine-loaded PLGA nanoparticles.Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation.Evodiamine inhibits adipogenesis via the EGFR-PKCalpha-ERK signaling pathway.Tumor suppressor TSLC1 is implicated in cell proliferation, invasion and apoptosis in laryngeal squamous cell carcinoma by regulating Akt signaling pathway.Propionyl-L-carnitine reduces proliferation and potentiates Bax-related apoptosis of aortic intimal smooth muscle cells by modulating nuclear factor-kappaB activity.Evodiamine Inhibits Zymosan-Induced Inflammation In Vitro and In Vivo: Inactivation of NF-κB by Inhibiting IκBα Phosphorylation.The role of propranolol as a radiosensitizer in gastric cancer treatment.Suppression of the NF‑κB signaling pathway in colon cancer cells by the natural compound Riccardin D from Dumortierahirsute.
P2860
Q22299231-36747A80-3BA6-4DF1-BA52-12107BFBCC9CQ23912834-CB2EF873-47BE-4CCB-8B6C-D4245ABBBEF9Q24631327-AC5BA71E-42BC-48AC-93AC-ACF62CB187C7Q26753053-B8F02201-6D17-4397-BF84-C16BD423A164Q27340176-E4BF03F6-6504-487B-9BD2-4D4F7325DFC2Q28484247-2816C700-D378-4BE2-8800-7FBDD4E5F872Q28538867-83BEC89F-5883-4946-9E13-99DE070B657FQ28542722-49A9DF5F-796C-4FA3-A5F5-B107403AD552Q30379103-036984A9-A268-49E7-8C67-EFEBB178C63DQ33954715-840AC8C3-CF95-4B2F-9E78-4CA1D452F7C6Q34116837-91A0C062-0C60-4545-BE7F-7B66E34DA21AQ34283058-03BA8D83-47DC-4EC0-AD0A-519F637C3C83Q34588342-AB2079B2-2A3B-403F-B1DC-85E053E5DFC6Q34806990-15230485-BDA9-4FA4-8D6E-2C898A960FB2Q35114614-DB508FBE-8C1E-464D-B3AA-7D8E18335D6AQ35143597-9068E3E4-E26C-4235-809C-99BDB57E4741Q35210044-9413686D-60A4-4A9B-89E3-BF6B756174E5Q35578720-D490251B-A003-410E-8A63-2463F36D1BB5Q35685370-AB25A4A4-35B2-4AD6-81EE-3CA4CAA4B781Q35856573-6D273282-39FE-4DF8-A6E8-7261CA9E3B6DQ36261565-2F6BE285-B6E0-4601-9CBA-6361100B5FD3Q36587800-6FBAFCF0-1007-4124-847B-DAABBDBBFE51Q36790190-67BF8F8D-D99F-4DA2-B3F6-5360BDD56EB8Q37154117-1644E22E-0377-4B36-8EBE-844F827D3ABBQ37184739-365B64E8-EE34-490A-A46E-F1F68AAB12CCQ37265616-6C1035F6-85AE-4E3E-8156-99D28FB9F542Q37882459-B4282D04-7E53-4E6C-A645-ABFC7BE608A6Q37990470-CAF66687-24B6-4D17-89FF-56FD983DD548Q38345920-D7205B91-ABC8-4546-A07C-5EB7E615425FQ38821356-71228A5F-B099-4BDC-9715-AACCCA7D3B0FQ38888042-6ED4FCF0-E120-4AC1-B1DA-C8CAA34B3A69Q38945383-B22C4A07-A989-449D-9EC0-4A0D2B6414DFQ38987697-73ECE700-EDA9-42DD-AB62-0FCE5BA04700Q41573009-022B891C-1363-4942-997C-99B27895C879Q42832797-89EFACE4-2605-4B25-A18C-01B634184AC1Q46208226-77C5DAB4-0260-4BD0-A474-8E6F95FFBE4DQ48082727-63676C0B-0E48-4145-9D0E-F96A8EB4580EQ51088688-8396C28C-F240-40FD-B168-FD408F51D66CQ52595303-1909080E-B943-45E2-A913-D7DBF4BC3B4CQ52684026-455FEEE2-298A-4FBD-8B5B-EF46FFD0303A
P2860
Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Evodiamine abolishes constitut ...... tosis, and inhibiting invasion
@en
type
label
Evodiamine abolishes constitut ...... tosis, and inhibiting invasion
@en
prefLabel
Evodiamine abolishes constitut ...... tosis, and inhibiting invasion
@en
P2093
P2860
P356
P1476
Evodiamine abolishes constitut ...... tosis, and inhibiting invasion
@en
P2093
Bharat B Aggarwal
Yasunari Takada
Yoshinori Kobayashi
P2860
P304
17203-17212
P356
10.1074/JBC.M500077200
P407
P577
2005-02-14T00:00:00Z