Efficient Generation of Gene-Modified Pigs Harboring Precise Orthologous Human Mutation via CRISPR/Cas9-Induced Homology-Directed Repair in Zygotes.
about
CRISPR/Cas9-mediated ApoE-/- and LDLR-/- double gene knockout in pigs elevates serum LDL-C and TC levels.Efficient Genome Editing in Chicken DF-1 Cells Using the CRISPR/Cas9 SystemTargeted Gene Knockin in Porcine Somatic Cells Using CRISPR/Cas Ribonucleoproteins.Application of the genome editing tool CRISPR/Cas9 in non-human primates.Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair.Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases.In vivo and in vitro disease modeling with CRISPR/Cas9.Modification of the Genome of Domestic Animals.Developmental competence of porcine genome-edited zygotes.Genome editing and genetic engineering in livestock for advancing agricultural and biomedical applications.Targeted gene knock-in by CRISPR/Cas ribonucleoproteins in porcine zygotes.Importance of oil overlay for production of porcine embryos in vitro.Use of gene-editing technology to introduce targeted modifications in pigs.Genetically engineered pigs as models for human disease.In vivo genome editing thrives with diversified CRISPR technologies.Successful knock-in of Hypertrophic Cardiomyopathy-mutation R723G into the MYH7 gene mimics HCM pathology in pigs.Generation of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer.Key Genes and Pathways Associated With Inner Ear Malformation in SOX10 p.R109W Mutation Pigs.High fidelity CRISPR/Cas9 increases precise monoallelic and biallelic editing events in primordial germ cellsGenome Editing of Pigs for Agriculture and BiomedicineCRISPR/Cas9-Mediated Generation of Guangxi Bama Minipigs Harboring Three Mutations in α-Synuclein Causing Parkinson's Disease
P2860
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P2860
Efficient Generation of Gene-Modified Pigs Harboring Precise Orthologous Human Mutation via CRISPR/Cas9-Induced Homology-Directed Repair in Zygotes.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Efficient Generation of Gene-M ...... gy-Directed Repair in Zygotes.
@en
type
label
Efficient Generation of Gene-M ...... gy-Directed Repair in Zygotes.
@en
prefLabel
Efficient Generation of Gene-M ...... gy-Directed Repair in Zygotes.
@en
P2093
P2860
P356
P1433
P1476
Efficient Generation of Gene-M ...... gy-Directed Repair in Zygotes.
@en
P2093
Chuanhong Liu
Shibing Zhang
Shiqiang Wang
Xiaoyang Zhou
Xingxu Huang
P2860
P304
P356
10.1002/HUMU.22913
P577
2015-10-07T00:00:00Z