Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1.
about
Enhancers: five essential questionsMediator and cohesin connect gene expression and chromatin architectureCTCF-dependent enhancer-blocking by alternative chromatin loop formationThe Chromatin Signature of Pluripotency: Establishment and MaintenanceThe second decade of 3C technologies: detailed insights into nuclear organizationMaster regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignanciesGetting the genome in shape: the formation of loops, domains and compartmentsAn Overview of Genome Organization and How We Got There: from FISH to Hi-CMechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathiesThe complex transcription regulatory landscape of our genome: control in three dimensionsHematopoietic overexpression of FOG1 does not affect B-cells but reduces the number of circulating eosinophilsBeta-globin LCR and intron elements cooperate and direct spatial reorganization for gene therapyDNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene RegulationLong-range communication between the silencers of HMR.DNA looping facilitates targeting of a chromatin remodeling enzyme.β-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapiesChromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elementsErythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expressionDiscovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancyControlling long-range genomic interactions at a native locus by targeted tethering of a looping factorGATA switches as developmental driversGATA-1 associates with and inhibits p53.Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteinsMultiple functions of Ldb1 required for beta-globin activation during erythroid differentiationSpecific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongationCTCF mediates long-range chromatin looping and local histone modification in the beta-globin locusSCL and associated proteins distinguish active from repressive GATA transcription factor complexesPdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene.A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement.Finding cis-regulatory elements using comparative genomics: some lessons from ENCODE data.Maintenance of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription.Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte.Inter-MAR association contributes to transcriptionally active looping events in human beta-globin gene cluster.Chromatin conformation signatures of cellular differentiationAll of the human beta-type globin genes compete for LCR enhancer activity in embryonic erythroid cells of yeast artificial chromosome transgenic miceH4R3 methylation facilitates beta-globin transcription by regulating histone acetyltransferase binding and H3 acetylationTranscriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.Role of LDB1 in the transition from chromatin looping to transcription activation.A downstream intergenic cluster of regulatory enhancers contributes to the induction of CYP24A1 expression by 1alpha,25-dihydroxyvitamin D3.
P2860
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P2860
Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Proximity among distant regula ...... cus requires GATA-1 and FOG-1.
@en
type
label
Proximity among distant regula ...... cus requires GATA-1 and FOG-1.
@en
prefLabel
Proximity among distant regula ...... cus requires GATA-1 and FOG-1.
@en
P2093
P1433
P1476
Proximity among distant regula ...... cus requires GATA-1 and FOG-1.
@en
P2093
Danielle L Letting
Gerd A Blobel
Job Dekker
M A Bender
Mark Groudine
Nele Gheldof
Tomoyuki Sawado
P304
P356
10.1016/J.MOLCEL.2004.12.028
P577
2005-02-01T00:00:00Z