Protons trap NR1/NR2B NMDA receptors in a nonconducting state.
about
Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disordersGlutamate receptor ion channels: structure, regulation, and functionGluN1-specific redox effects on the kinetic mechanism of NMDA receptor activationEffects of NR1 splicing on NR1/NR3B-type excitatory glycine receptorsStationary gating of GluN1/GluN2B receptors in intact membrane patchesStructural determinants of D-cycloserine efficacy at the NR1/NR2C NMDA receptorsControl of assembly and function of glutamate receptors by the amino-terminal domain.Extracellular Ca(2+) ions reduce NMDA receptor conductance and gating.Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na⁺/H⁺ exchanger NHE5Does anesthetic additivity imply a similar molecular mechanism of anesthetic action at N-methyl-D-aspartate receptors?Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects.Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis.Extracellular proton-modulated pore-blocking effect of the anticonvulsant felbamate on NMDA channelsA steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protonsAcid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons.C-terminal domains of N-methyl-D-aspartic acid receptor modulate unitary channel conductance and gatingIfenprodil effects on GluN2B-containing glutamate receptors.Constitutive activation of the N-methyl-D-aspartate receptor via cleft-spanning disulfide bonds.Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potentialMolecular basis of NMDA receptor functional diversity.Investigational NMDA receptor modulators for depression.Modes of glutamate receptor gating.The paradox of the paroxysm: can seizure precipitants help explain human ictogenesis?Endosomal pH in neuronal signaling and synaptic transmission: role of Na(+)/H(+) exchanger NHE5.Zinc inhibition of rat NR1/NR2A N-methyl-D-aspartate receptors.Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block.Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors.Conserved structural and functional control of N-methyl-D-aspartate receptor gating by transmembrane domain M3.Dopamine D1 receptor inhibition of NMDA receptor currents mediated by tyrosine kinase-dependent receptor trafficking in neonatal rat striatum.GluN2B and GluN2D NMDARs dominate synaptic responses in the adult spinal cordActions of bupivacaine, a widely used local anesthetic, on NMDA receptor responses.GluN1 splice variant control of GluN1/GluN2D NMDA receptors.Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits.Allosteric Inhibitors of NMDA Receptor Functions.NMDA Receptors in the Central Nervous System.Disease-associated missense mutations in GluN2B subunit alter NMDA receptor ligand binding and ion channel properties.
P2860
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P2860
Protons trap NR1/NR2B NMDA receptors in a nonconducting state.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
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2005年學術文章
@zh-hant
name
Protons trap NR1/NR2B NMDA receptors in a nonconducting state.
@en
type
label
Protons trap NR1/NR2B NMDA receptors in a nonconducting state.
@en
prefLabel
Protons trap NR1/NR2B NMDA receptors in a nonconducting state.
@en
P1476
Protons trap NR1/NR2B NMDA receptors in a nonconducting state
@en
P2093
Shashank M Dravid
Stephen F Traynelis
P356
10.1523/JNEUROSCI.3154-04.2005
P407
P50
P577
2005-01-01T00:00:00Z