Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase - Wikidata - wikimedia - TriplyDB

Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase

Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase

http://www.wikidata.org/entity/Q40483619

about

Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeleton Etiology and early pathogenesis of malignant testicular germ cell tumors: towards possibilities for preinvasive diagnosis The VASP-Spred-Sprouty domain puzzle.The developing story of Sprouty and cancer.Mammalian sprouty proteins assemble into large monodisperse particles having the properties of intracellular nanobatteries.Sprouty4 is an endogenous negative modulator of TrkA signaling and neuronal differentiation induced by NGF Sprouty4, a suppressor of tumor cell motility, is down regulated by DNA methylation in human prostate cancer.Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.Sprouty is a cytoplasmic target of adenoviral E1A oncoproteins to regulate the receptor tyrosine kinase signalling pathway The parvins.Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src.Tau-based treatment strategies in neurodegenerative diseases Intermolecular interactions of Sprouty proteins and their implications in development and disease.Testicular germ cell tumours: predisposition genes and the male germ cell niche.Sprouty4 interferes with cell proliferation and migration of breast cancer-derived cell lines.Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin-proteasome pathway.Sprouty 2 protein, but not Sprouty 4, is an independent prognostic biomarker for human epithelial ovarian cancer.

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P2860

Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase

http://www.wikidata.org/entity/Q40483619

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Sprouty-4 negatively regulates ...... y of testicular protein kinase

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type

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Sprouty-4 negatively regulates ...... y of testicular protein kinase

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Biochemical Journal

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Sprouty-4 negatively regulates ...... y of testicular protein kinase

@en

P2093

Jiro Toshima

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Kazumasa Ohashi

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Kensaku Mizuno

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Onno C Leeksma

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Yoshikazu Tsumura

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P2860

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1

Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs

sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505

Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation

Identification and characterization of a novel protein kinase, TESK1, specifically expressed in testicular germ cells

Dual specificity protein kinase activity of testis-specific protein kinase 1 and its regulation by autophosphorylation of serine-215 within the activation loop

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627-637

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scholarly article

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10.1042/BJ20041181

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P433

Pt 3

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P478

387

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2005-05-01T00:00:00Z

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8142869

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15584898

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1134992

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