Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line.
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Cooperative epigenetic modulation by cancer amplicon genesNegative regulation of cytokine signaling and immune responses by SOCS proteinsThe role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancerSOCS, inflammation, and cancerThe role of suppressors of cytokine signalling in human neoplasmsThe JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemiaNovel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive reviewPrimary mediastinal B-cell lymphoma: treatment and therapeutic targetsSTAT6 expression in glioblastoma promotes invasive growthJAK2 V617F in myeloid disorders: what do we know now, and where are we headed?Suppressor of cytokine signaling 1 gene expression and polymorphisms in systemic lupus erythematosus.Diffuse large B-cell lymphoma: can genomics improve treatment options for a curable cancer?Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma.JAK2 V617F detected in two B-cell chronic lymphocytic leukemia patients without coexisting Philadelphia chromosome-negative myeloproliferative neoplasms: A report of two cases.FOXO1 downregulation contributes to the oncogenic program of primary mediastinal B-cell lymphoma.Primary mediastinal large B-cell lymphoma.Phase I study of a novel oral Janus kinase 2 inhibitor, SB1518, in patients with relapsed lymphoma: evidence of clinical and biologic activity in multiple lymphoma subtypes.Targeting the JAK-STAT pathway in lymphoma: a focus on pacritinib.Primary mediastinal B-cell lymphoma and mediastinal gray zone lymphoma: do they require a unique therapeutic approach?Suppressor of cytokine signaling 1 gene mutation status as a prognostic biomarker in classical Hodgkin lymphoma.Loss of major histocompatibility class II gene and protein expression in primary mediastinal large B-cell lymphoma is highly coordinated and related to poor patient survival.Genomic Landscape of Primary Mediastinal B-Cell Lymphoma Cell Lines.Mechanisms of B-cell lymphoma pathogenesis.Constitutive Activation of Interleukin-13/STAT6 Contributes to Kaposi's Sarcoma-Associated Herpesvirus-Related Primary Effusion Lymphoma Cell Proliferation and Survival.A requirement for SOCS-1 and SOCS-3 phosphorylation in Bcr-Abl-induced tumorigenesis.SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation.Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development.The role of Janus kinases in haemopoiesis and haematological malignancy.The molecular biology of diffuse large B-cell lymphoma.SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients.STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL).JAK2 mutants (e.g., JAK2V617F) and their importance as drug targets in myeloproliferative neoplasmsCommentary on the WHO classification of tumors of lymphoid tissues (2008): "Gray zone" lymphomas overlapping with Burkitt lymphoma or classical Hodgkin lymphoma.No evidence for the JAK2 (V617F) or JAK2 exon 12 mutations in primary mediastinal large B-cell lymphoma.New insights into the regulation of human B-cell differentiation.Primary mediastinal DLBCL: evolving biologic understanding and therapeutic strategies.JAK2 inhibition for the treatment of hematologic and solid malignancies.Gray zone lymphoma: better treated like hodgkin lymphoma or mediastinal large B-cell lymphoma?Whole genome profiling and other high throughput technologies in lymphoid neoplasms--current contributions and future hopes.SOCS proteins in development and disease.
P2860
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P2860
Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Biallelic mutation of SOCS-1 i ...... B-1 mediastinal lymphoma line.
@en
type
label
Biallelic mutation of SOCS-1 i ...... B-1 mediastinal lymphoma line.
@en
prefLabel
Biallelic mutation of SOCS-1 i ...... B-1 mediastinal lymphoma line.
@en
P2093
P1433
P1476
Biallelic mutation of SOCS-1 i ...... B-1 mediastinal lymphoma line.
@en
P2093
Alexandra Juliana Bucur
Cornelia Hasel
Frank Leithäuser
Ingo Melzner
Karola Dorsch
Peter Möller
Silke Brüderlein
Thomas F E Barth
P304
P356
10.1182/BLOOD-2004-09-3701
P407
P577
2004-11-30T00:00:00Z