Activity of the Aurora kinase inhibitor VX-680 against Bcr/Abl-positive acute lymphoblastic leukemias.
about
Phosphoflow-Based Evaluation of Mek Inhibitors as Small-Molecule Therapeutics for B-Cell Precursor Acute Lymphoblastic LeukemiaExpression of cassini, a murine gamma-satellite sequence conserved in evolution, is regulated in normal and malignant hematopoietic cellsOn the importance of composite protein multiple ligand interactions in protein pockets.Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell deathDirect and indirect targeting of MYC to treat acute myeloid leukemiaA phase I study of danusertib (PHA-739358) in adult patients with accelerated or blastic phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant or intolerant to imatinib and/or other second generatBioinformatics and variability in drug response: a protein structural perspective.Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib)O-acetylated N-acetylneuraminic acid as a novel target for therapy in human pre-B acute lymphoblastic leukemia.Adipocytes cause leukemia cell resistance to L-asparaginase via release of glutamine.Therapy of chronic myeloid leukemia: twilight of the imatinib era?Janus kinase 2 inhibitors in myeloproliferative disorders.High chromosome number in hematological cancer cell lines is a negative predictor of response to the inhibition of Aurora B and C by GSK1070916.ENMD-2076 for hematological malignancies.JAK2 inhibition for the treatment of hematologic and solid malignancies.Pediatric relapsed or refractory leukemia: new pharmacotherapeutic developments and future directions.Glutaminase activity determines cytotoxicity of L-asparaginases on most leukemia cell lines.B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3.Aurora-A Kinase: A Potent Oncogene and Target for Cancer Therapy.Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.Cytotoxicity of CD56-positive lymphocytes against autologous B-cell precursor acute lymphoblastic leukemia cellsCombination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist.Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008.MK-0457, an Aurora kinase and BCR-ABL inhibitor, is active in patients with BCR-ABL T315I leukemia.
P2860
Q28547880-0E92915D-3085-4FAA-B315-E69A8D9E6640Q28710528-2D8CB733-42FE-4F26-A3AF-4B62CF2B5E31Q33599179-221DAF6A-66D7-43E7-A270-0753DDA7D1BFQ35476091-1CECB0D3-1DCD-4D8C-95B9-05C6D5A59AC6Q35798798-C227A32B-C979-4672-940A-D2E96D69D659Q35800825-C40DEF60-D07F-4BEA-A051-3C604554BEA7Q36009999-8C01C3D9-3FC3-4FD2-B53F-F13437DEA3E1Q36373227-388F812E-9F57-4CA6-A6FE-430A93C60FCBQ36750016-83F754FE-A5F5-4369-8BDE-154FC42E1B73Q36933370-0F6A67AE-37CD-4033-AC3C-C4FE6C0ED15FQ37593435-AFE9909F-1241-499F-BB7A-A813E434668CQ37815509-C034DF82-9E9F-40EE-8482-37391BCED3A5Q37901574-0D9639AB-30A2-4169-90F4-BC45A157B59EQ37991379-B8C0A6EB-753B-4934-B5F1-7D82E282FD30Q38001733-7584B2EE-3357-4323-A5C2-4E9F234A56F5Q38097334-76FCBDD4-395C-4687-96CF-2513FC813112Q38879052-01C9E221-5C8A-48FB-86DC-B42A1D7029D1Q38887855-2886FAFF-BD01-4C5A-8947-35ABEE094AD1Q38894287-B1AA1C05-FEB1-4BF5-90BA-2786E5A4468EQ39429784-8C2532B9-FEC4-4C27-86A7-5DF5499D83DEQ42556477-F25FC4B1-3310-4F97-905F-05E2324F5E82Q42803194-B655CB19-10F0-45BE-9E39-F77FF6D39687Q52724033-37AD1FAE-FA7D-4D60-ABCC-508C0F0EEB71Q54498929-2802CDFF-E3DF-488A-9922-133A8E5461B5
P2860
Activity of the Aurora kinase inhibitor VX-680 against Bcr/Abl-positive acute lymphoblastic leukemias.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Activity of the Aurora kinase ...... acute lymphoblastic leukemias.
@en
type
label
Activity of the Aurora kinase ...... acute lymphoblastic leukemias.
@en
prefLabel
Activity of the Aurora kinase ...... acute lymphoblastic leukemias.
@en
P2093
P2860
P1476
Activity of the Aurora kinase ...... acute lymphoblastic leukemias.
@en
P2093
John Groffen
Nora Heisterkamp
Sonia Stoddart
P2860
P304
P356
10.1158/1535-7163.MCT-10-0069
P577
2010-04-13T00:00:00Z