TccP is an enterohaemorrhagic Escherichia coli O157:H7 type III effector protein that couples Tir to the actin-cytoskeleton.
about
A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosisRecognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assemblyInsulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formationMolecular basis of actin reorganization promoted by binding of enterohaemorrhagic Escherichia coli EspB to alpha-cateninDistinct phosphorylation requirements regulate cortactin activation by TirEPEC and its binding to N-WASPCommensal and pathogenic Escherichia coli use a common pilus adherence factor for epithelial cell colonizationAn extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their disseminationBioinformatics analysis of the locus for enterocyte effacement provides novel insights into type-III secretionVisualizing the Translocation and Localization of Bacterial Type III Effector Proteins by Using a Genetically Encoded Reporter System.Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspFUEnterohaemorrhagic Escherichia Coli Exploits a Tryptophan Switch to Hijack Host F-Actin AssemblyThe QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC)NsrR, GadE, and GadX interplay in repressing expression of the Escherichia coli O157:H7 LEE pathogenicity island in response to nitric oxideEnteropathogenic Escherichia coli and vaccinia virus do not require the family of WASP-interacting proteins for pathogen-induced actin assemblyMembrane-deforming proteins play distinct roles in actin pedestal biogenesis by enterohemorrhagic Escherichia coli.Comparative analysis of the biochemical and functional properties of C-terminal domains of autotransportersPhysical mechanisms of signal integration by WASP family proteins.Hierarchical regulation of WASP/WAVE proteins.Cortactin recruitment by enterohemorrhagic Escherichia coli O157:H7 during infection in vitro and ex vivo.A novel two-component signaling system that activates transcription of an enterohemorrhagic Escherichia coli effector involved in remodeling of host actin.Cortactin is essential for F-actin assembly in enteropathogenic Escherichia coli (EPEC)- and enterohaemorrhagic E. coli (EHEC)-induced pedestals and the alpha-helical region is involved in the localization of cortactin to bacterial attachment sites.The Type Three Secretion System 2-Encoded Regulator EtrB Modulates Enterohemorrhagic Escherichia coli Virulence Gene Expression.The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways.The localized adherence pattern of an atypical enteropathogenic Escherichia coli is mediated by intimin omicron and unexpectedly promotes HeLa cell invasion.Global transcriptional response of Escherichia coli O157:H7 to growth transitions in glucose minimal medium.Repetitive N-WASP-binding elements of the enterohemorrhagic Escherichia coli effector EspF(U) synergistically activate actin assembly.Intestinal damage in enterohemorrhagic Escherichia coli infection.Shiga toxin in enterohemorrhagic E.coli: regulation and novel anti-virulence strategiesGlobal analysis of posttranscriptional regulation by GlmY and GlmZ in enterohemorrhagic Escherichia coli O157:H7The T3SS effector EspT defines a new category of invasive enteropathogenic E. coli (EPEC) which form intracellular actin pedestals.Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivoTwo atypical enteropathogenic Escherichia coli strains induce the production of secreted and membrane-bound mucins to benefit their own growth at the apical surface of human mucin-secreting intestinal HT29-MTX cellsEnterohemorrhagic E. coli requires N-WASP for efficient type III translocation but not for EspFU-mediated actin pedestal formation.Direct injection of functional single-domain antibodies from E. coli into human cells.EspJ is a prophage-carried type III effector protein of attaching and effacing pathogens that modulates infection dynamics.Bacterial and host determinants of MAL activation upon EPEC infection: the roles of Tir, ABRA, and FLRT3SepZ/EspZ is secreted and translocated into HeLa cells by the enteropathogenic Escherichia coli type III secretion systemThe EHEC type III effector NleL is an E3 ubiquitin ligase that modulates pedestal formation.TccP2-mediated subversion of actin dynamics by EPEC 2 - a distinct evolutionary lineage of enteropathogenic Escherichia coliA transcriptome study of the QseEF two-component system and the QseG membrane protein in enterohaemorrhagic Escherichia coli O157 : H7.
P2860
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P2860
TccP is an enterohaemorrhagic Escherichia coli O157:H7 type III effector protein that couples Tir to the actin-cytoskeleton.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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name
TccP is an enterohaemorrhagic ...... Tir to the actin-cytoskeleton.
@en
type
label
TccP is an enterohaemorrhagic ...... Tir to the actin-cytoskeleton.
@en
prefLabel
TccP is an enterohaemorrhagic ...... Tir to the actin-cytoskeleton.
@en
P2093
P2860
P50
P1476
TccP is an enterohaemorrhagic ...... Tir to the actin-cytoskeleton.
@en
P2093
Alan D Phillips
Eric Oswald
Junkal Garmendia
Olivier Marches
Rob K Shaw
Sivan Dahan
Stuart Knutton
Yuwen Chong
P2860
P304
P356
10.1111/J.1462-5822.2004.00459.X
P577
2004-12-01T00:00:00Z