Novel mechanism of interaction of p85 subunit of phosphatidylinositol 3-kinase and ErbB3 receptor-derived phosphotyrosyl peptides.
about
Targeting of erbB3 receptor to overcome resistance in cancer treatmentVascular endothelial growth factor receptor 1 contributes to Escherichia coli K1 invasion of human brain microvascular endothelial cells through the phosphatidylinositol 3-kinase/Akt signaling pathway.Profiling epidermal growth factor receptor and heregulin receptor 3 heteromerization using receptor tyrosine kinase heteromer investigation technology.Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells.ErbB receptors and epithelial-cadherin-catenin complex in human carcinomas.The ERBB3 receptor in cancer and cancer gene therapyStructural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop.Molecular dynamics simulations reveal that Tyr-317 phosphorylation reduces Shc binding affinity for phosphotyrosyl residues of epidermal growth factor receptorHER3/ErbB3, an emerging cancer therapeutic target.HER3 Targeting Sensitizes HNSCC to Cetuximab by Reducing HER3 Activity and HER2/HER3 Dimerization: Evidence from Cell Line and Patient-Derived Xenograft Models.Anti-HER3 Monoclonal Antibody Inhibits Acquired Trastuzumab-Resistant Gynecologic Cancers.ERBB3 (HER3) is a key sensor in the regulation of ERBB-mediated signaling in both low and high ERBB2 (HER2) expressing cancer cells.siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cellsHER3 intracellular domains play a crucial role in HER3/HER2 dimerization and activation of downstream signaling pathways.A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: activation-dependent regulation of ERK by p85 in multiple myeloma cells.N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase.
P2860
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P2860
Novel mechanism of interaction of p85 subunit of phosphatidylinositol 3-kinase and ErbB3 receptor-derived phosphotyrosyl peptides.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Novel mechanism of interaction ...... rived phosphotyrosyl peptides.
@en
type
label
Novel mechanism of interaction ...... rived phosphotyrosyl peptides.
@en
prefLabel
Novel mechanism of interaction ...... rived phosphotyrosyl peptides.
@en
P2093
P2860
P50
P356
P1476
Novel mechanism of interaction ...... erived phosphotyrosyl peptides
@en
P2093
Akihiko Konagaya
Atsushi Suenaga
Mariko Hatakeyama
Mikako Shirouzu
Mio Ichikawa
Naoki Takada
Noriaki Okimoto
Noriyuki Futatsugi
Tetsu Narumi
Xiaomei Yu
P2860
P304
P356
10.1074/JBC.M410436200
P407
P577
2004-11-01T00:00:00Z